#Streptococcus pyogenes M1 476 (25 genes)
Gene	Start	Stop	Strand	Original description	class	type	P2CS description	tm
M1GAS476_0308	273422	274984	+	sensory transduction protein kinase	HK	Classic	Histidine kinase, Classic contains 1 HisKA_MA, 1 HATPase_c	11
M1GAS476_0309	274965	275570	+	transcriptional regulatory protein	RR	NarL	Response regulator, NarL family contains 1 Response_reg,1 HTH_LUXR	0
M1GAS476_0346	311195	311881	+	response regulator	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
M1GAS476_0347	311887	313389	+	transmembrane histidine kinase	HK	Classic	Histidine kinase, Classic contains 1 HAMP,1 HisKA,1 HATPase_c	2
M1GAS476_0492	447087	447797	+	two-component response regulator	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
M1GAS476_0493	447790	449142	+	two-component sensor histidine kinase	HK	Classic	Histidine kinase, Classic contains 1 PAS,1 HisKA,1 HATPase_c	2
M1GAS476_0739	701168	701836	+	two-component response regulator	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
M1GAS476_0740	701818	703077	+	two-component system histidine kinase	HK	Classic	Histidine kinase, Classic contains 1 HisKA,1 HATPase_c	3
M1GAS476_0844	806716	808365	+	two-component sensor kinase	HK	Classic	Histidine kinase, Classic contains 1 HAMP,1 His_kinase,1 HATPase_c	3
M1GAS476_0845	808369	809157	+	two-component response regulator	RR	YesN	Response regulator, YesN family contains 1 Response_reg,1 HTH_AraC	0
M1GAS476_0861	823697	824383	+	nisin biosynthesis two-component response                     regulator	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
M1GAS476_0862	824361	825722	+	nisin biosynthesis sensor protein	HK	Classic	Histidine kinase, Classic contains 1 HisKA,1 HATPase_c	3
M1GAS476_0887	842356	843021	-	transcriptional regulatory protein	RR	unclassified	Response regulator, unclassified contains 1 Response_reg	0
M1GAS476_1005	955197	956507	-	sensor protein	HK	Classic	Histidine kinase, Classic contains 1 HisKA,1 HATPase_c	3
M1GAS476_1006	956500	957174	-	transcriptional regulatory protein	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
M1GAS476_1345	1253294	1255027	-	two-component sensor kinase	HK	Classic	Histidine kinase, Classic contains 1 Cache_1,1 HAMP,1 His_kinase,1 HATPase_c	1
M1GAS476_1346	1255024	1255764	-	two-component response regulator	RR	YesN	Response regulator, YesN family contains 1 Response_reg,2 HTH_AraC	0
M1GAS476_1372	1280539	1282026	-	two-component response regulator	RR	YesN	Response regulator, YesN family contains 1 Response_reg,2 HTH_AraC	0
M1GAS476_1373	1282023	1283750	-	two-component sensor kinase	HK	Classic	Histidine kinase, Classic contains 1 HAMP,1 His_kinase,1 HATPase_c	1
M1GAS476_1408	1316985	1317632	-	two-component response regulator	RR	NarL	Response regulator, NarL family contains 1 Response_reg,1 HTH_LUXR	0
M1GAS476_1409	1317619	1318623	-	two-component sensor protein	HK	Classic	Histidine kinase, Classic contains 1 HisKA_3,1 HATPase_c	2
M1GAS476_1749	1649693	1650433	-	response regulator	RR	LytTR	Response regulator, LytTR family contains 1 Response_reg,1 LytTR	0
M1GAS476_1751	1651717	1653063	-	sensory transduction protein kinase	HK	Classic	Histidine kinase, Classic contains 1 HisKA_MA, 1 HATPase_c	8
M1GAS476_1775	1681964	1683352	-	two component system histidine kinase	HK	Classic	Histidine kinase, Classic contains 1 HAMP,1 HisKA,1 HATPase_c	1
M1GAS476_1776	1683349	1684002	-	two-component response regulator	RR	OmpR	Response regulator, OmpR family contains 1 Response_reg,1 Trans_reg_C	0
