>NIDE0165_RR_NarL|Candidatus Nitrospira defluvii
MEKIKVLIADDHRVVREGLAAILKTKDDINVVGEAQDGVEAVEKTKTLMPDVILMDVSMP
RMGGIEATRQIKREFPHMGIVALTMYEEQQYIFDLVRAGATGYLLKDSESSQIVAAIRAI
YRGESLIHPSVASKILAEFSLMSQKKGKKPAWVEHDLTEREITVLRLVADGKTNKEIANN
LDLSEKTVKNHVRNIFHKLQVYDRTQAAILAIRKGLIELEPRP
>NIDE0166_HK_Classic|Candidatus Nitrospira defluvii
MTTTKVTRNRRTVKRPSRRRSPGATHVVIIGAGRGGTALMEIFANDPLVRIVGVADISDQ
APGLGLAKRLHIRVTRNYRQLLKMGPVDLVIDVSGNPEVGEYLQDIRRMGVSVIGGASAK
FMWQLIEARIRATADIEKALNKYQSLYRLYVKETGAAVTEERTRIACEIHDGLVQSLAGV
NFKLELSQELLRKNPKASLATIRESKAQLKLAIQEARQVIFNLRPLHYDKMELIPALTNY
LKSYETQYHIKTAFSVTGDETILFPRTKIFLFRIVQEALSNVQKHAKAGRVSVQLDIRLD
LLQVTISDNGIGFDMDAVLRDPEKWDHFGIRGILERARLVGGEATIDSKKGRGTRIVLRI
PLADKETIRHGKN
>NIDE0222_HK_Hybrid|Candidatus Nitrospira defluvii
MTQPLRFVHLESNPADAELVATTLRDAGIQCQLKQAPTREEFLAALRQEGFSLILADTTV
PGFDGAAALSLARTLHPDVPFLFVSGTQGEEFAIDMMQHGATDYISKQRLGRLVPSVKRT
LRELDERLERRRAEDALRVSEKQFRQAQKMEAVGRLAGGLAHDFNNLLTVIMGHSQVLMG
ELPSGNPIRAKIEEMQKAGERAASLIRQLMAFSRKQPLEPKILPLNSVVGNVESMLRRLI
GEDIQLVIRPDPFNGHVKADPGQLEQVLMNLVVNARDAMPNGGLLAIETSQTELARTPMH
HLHPLPLGQYVKLTVTDTGCGMNADVLAHLFEPFFTTKEEHKGTGLGLSTVFGIVTTCGG
GIDVWSQVGHGTTFDLYFPRVNPQAPTADATAPQGRLRQGSETILLVEDDSGVRNLVRHE
LVKTGYQVIEAKNGVEACLTATQQSYHVDLLLTDVVMPGMNGRELAQHLSVIKPNLRVLF
MSGYLDDISVNSGMDPHRTTFLQKPFTPDLLLRTVRALLDSSAPATGSAPHHFPPDQAPR
TARAS
>NIDE0223_RR_CheY|Candidatus Nitrospira defluvii
MTLTKPILLAEDNPRDAELALAAMEEHHLADKVILCHDGAEVLDYLYCRGHFKARLQGNP
AVVLLDLKMPKVDGLEVLRTIKNDAALKPIPVVMLTSSREERDLVESYALGANAYVVKPV
EFHQFLKAVKELGVFWGMINEPPPEGASRATGR
>NIDE0224_HK_Classic|Candidatus Nitrospira defluvii
MGMDEPKPQQAVNTDVEAVLPALPWSARILSHLSVLGPLVLAFQKRSIEQRVLAGFGLVF
AGILVIFAISYRNMTVLIRNGHHDQRSHEFIQSLAATGEAIDDAENGHRRFLVTGDESYL
AAYNTLRERAPEYLGYLRELTEPDSIQRARVTQLEQLITQQLREERAAIDLRKETGFESV
RTMALAGVATTALDSARRLQAQMEQDETKALAQRVVESTTTTRSSIILLIIGALLLFVLL
AAVYYLIRHDITARRRIADELQRRGELLEAANKELEAFSYSVSHDLRAPLRHIDGYASLL
AKAASISLDDKAKRYLQTISESATRMGQLIDDLLVFSRMGRQEMLRGTVNLNQLIASVLH
DLRHDLQDRTISWTIAQLPEVTGDAAMLRQVFMNLVANAIKFTGTRPQATIEIGSRDNGQ
EEAVLFVRDNGVGFDMRYANKLFGVFQRLHRADEFEGTGIGLANVRRIIHRHGGKTWAEG
ALGEGATFYVSLPLARTSA
>NIDE0240_RR_CheY|Candidatus Nitrospira defluvii
MPSVLIVDDEEAIRRLIRSTLEQAGYHVREAADGKAGLSHYRQSPADLVIMDILMPDQDG
LESILTLRREFPEARIMAITGGSDMIGILNFLDVARMLGARRTLQKPFEMQQLLDAVQAE
IAG
>NIDE0241_HK_Classic|Candidatus Nitrospira defluvii
VTAQDVTTALPPSGDSSTVEALVRTLSGQASLGIFLSDPAGRTLYLNERLRRIAGLPVTA
TPGECWRNALAPEDHDPICSEWSGATSAERSFSREFRFRRSDGSLRWVMAEAFPLRTGGG
PSGGYVGIVRDITPRQLALDALHANEERYRTLAQQSPHAILVYADNVVLFINEAGARIFG
LAAAHPIEGRALCDFFPKEFLHDLPLAETMPVPPVERQLVRPDGMVIDVELTAAPVMFDG
HPAIQLLGTDITERKVIAGQLHRAKKMATVATLAGGIAHEFNNCLTAIMGFSDLALPSLV
PDSRVHGHIQQVILASKRARDLVTQMLMAGRQADGAKQPLSLDILLKETLRVLKMTLPES
ISLREWIPGATNPVLADPTQIHELCLNLLARAQQVMTISGGVLEVRLDNVGIDASMTGHD
LPLPPGQYVRLMISDTGEGIPPDVRTPNRYPLFALPPTGSSAGAGLGELQRIVSEHGGTL
RATSTAGQGTTIEVYLPAMLQPHQTVAQEPSCKRATSLTEAKEFLAEHDKER
>NIDE0304_HK_Classic|Candidatus Nitrospira defluvii
MPLRVRLTLWYGTALALILLTFSVVLYTITARGLRDQVDESLQETASAAVRSLEKRGFLP
LIDEDALLSQFPELTRIDKFFQIFSPTGTITIRSPNIRQHDVPLSRHALEAAFTGSTVFE
SARYPNEPPLRLVSVPIIYRGSLLYIVQVGTTLEGVEETLRRFLLVLVVMAPIALVVSLV
GGWFLAGRALRPVDSITIAAQRIAAGDLTQRLTSERSTDEIGRLTDTFNNMIARLETSFA
QIRQFSSDASHELRTPLTVMKGESELVLRRPRPVEDYIAVLESNLEEIDRMSRIVEELLF
LSRADLGQVKTECEPVRLEALVEDIQRQACLLGQERGVDVIMGTIQPATVRGDELRLREL
ILNIVDNAVKYSYPQGTVDIDLLVEGRTARLSVRDHGIGIPQDAHKQIFDRFFRTDDARA
HTKKGTGLGLAICAWIAEAHHGHIEVQSEIGQGSTFTIVLPLAPPTA
>NIDE0305_RR_OmpR|Candidatus Nitrospira defluvii
MRVLVVEDETKVGSFIKRALEEESYAVDLCEDGAQGLDMALSGSYDLIMIDLMLPSLPGL
EVLTRLRKEKIQTPVLILTAQSKVDQRVKGLDAGADDYLTKPFAIDELLARVRALLRRGT
AESSGTLQIDDLLLNPATREVTRGGQRIDLTVKEYALLEYFMRHAGRVLTRPMISDHVWN
QDFDTFTNVIDVYVNYLRNKIDRGRARKLIHTIRGSGYMLKVD
>NIDE0390_RR_PleD|Candidatus Nitrospira defluvii
MIKLLLVEDNPVDAQLTRDLLAEWPLDQFEITHAPILAEGLTRLSRDRFDVVLLDLSLPD
THGLSTVTQVLATSPGVPVVVLSGHDDHPLALKALQHGAQDYLVKGEGGTEFLARSILYA
IERKRAQERLTYLAQHDQLTGLINRALFRDRLIHAMARSKRKDHPLAIMLLDLDRFKAVN
DTLGHDVGDQLLKVVATRLLECVREVDTVARMGGDEFTAILEGISGVADVLVVAKRIVES
ISTPFEIGPHRISIGVSIGITLYPLDDEDIDELLRHADKAMYAAKQQGGSRFHFHSTTGQ
PPSGTPAPVR
>NIDE0542_HK_Hybrid|Candidatus Nitrospira defluvii
MRPPVLIVDDDPDIRESLTDMLGHEGYLVHSAASGTEALQQAKQTRYDAALLDIQLPDLN
GLSVLKVLMELDASLPVIILTGNVTPENTIGSLAKGAFAYLTKPYNSQELKAILRRAVSV
KGLTVRAEHVEEALQASEERFRALVESATDAMVLADQSGLIIWWNGAAERMFGYTKEDAL
GRPLTIMMPERFRAAHAAGVTRLAQGGTATIIGHTIELVGLTKTGDEFPIELSLASWRAS
DGMFFSGIIRNIARRKRAEESVVRLSHQNALILDSAGEGIFGLDPQGCVTFANATAARIL
GWSAAELIGKPLAPLLYRIANGNAARSPDPFCLCAALHDGAVHRIQNEAFARKDGSLFPV
QYVTSPIRERDRLVGAVVVFQDISARKQQENLQQAQLSVSHILAQAGTVEEAIPQLLHVA
GTMGAWDMALLWQCGRMGDQLTCHGSWIRPSHRWDEFLSVCRNSEFPPGMDFPGIAWASK
LPLWIPDALTDSRFTRAPTASRLGIHGACIVPIRTGSIIHGVLELYTEQRRPSDSHLIQI
LADTGMKIGQFIDRTRAAQALRAAHRTTQSLLASLPGAIFLCGSDLQVQYANALAHQYFA
LPGESLIGRPLCECLSLSEPALQRQVVEWNTHTADSPHRLSECECEVAARLYRYRFFPVS
TPESPQYQVGILLWDITDDKRLQDELIQAEKLSSLGTMVSGMAHEINNPAQAILSMAELI
QEEDDPDTVKQFAADIVGYARHVSTVVRDFAGYARAAGRDGETEIDVAERLLEAVKMVRR
GPHFGQVEIATQFDAPVFLRARKGEIDQVFVNLISNATQAMEGIGCLTLTTGQDGRWIQV
TIADTGPGIPASIRPRIFDPFFTTKTAGKGTGLGLSIVHKIVIKYAGTITVESTEGGGTT
FRLRFPALVQ
>NIDE0543_HK_Classic|Candidatus Nitrospira defluvii
MKGLTVKGPAHYLTSPSLYPSGPGRFVSLRTKFVVFFSLIIILTCSGMSWYFIHSKRIAM
TERVQDLGTILVKNLAHNVRYGIIIEERVILEQFIDGVMGVDEVVYALITGTDGQILAAK
SKGRLDSPLGTVRSTERPFYPRPDIAEAVIKRSGAEPTITHLRLSGADTIPLREKDSTLP
ISTSGIHVETFYDFAIPVMKRSESRLEALALQEEETRKAAIAPSTPQAFGVVQIGLTEVP
MQRELAKILRNFLLLTLGIITAGILCTNLLARRIITPLRHLAAGARKVSEGDLSTFVVPT
TQDEVGQLTALFNLMTKSLQERNQAISANLETIRRHVTQLTTLNQSSTAITSTLDLDRLL
SIVLQLLSANLGFARMVLFLWDSERGVATVGQMLGMPQEAEEAARRLEIPVYEDGGFAAE
LLIHGKPLFVPSIEPVADRISPAVLPWLRQVGISSFVAAPLRSQQRILGYLGADRGTQPC
SQEDLDLLITIASHVAVAVDNARAYTELATLTDHLERRVQERTHELQTVNERLQEHDQRR
SKFVSVASHELRTPMTSIKGFVENMLDGLTGQLSERQEHYLQRVKHNVDRLTRIINQLLD
WSRLDVGRIEIKPEPLHIDEFVRDVVESFQTLAAEKSIVLDVLPCEQPITVRADRDKLEQ
ILWNLVGNAIKFTPPSGHVSVSCSICDARYAQITVADTGCGIAPDELPHVFNEFSKVESA
MPSSQGAQLGLFITKSLVALHGGQMCVDSRLGVGTQFYFTLPLDNAPASTP
>NIDE0545_RR_unclassified|Candidatus Nitrospira defluvii
MTATTPGHSILVVDDDPDIALGLQDLLDHDGYHVSVAGTCAEALTQTHDHHYNAVLLDLG
LPDGDGSSVLRTLQEQQPQLPVIILTAYTSADRTVGSLTQGAFAYLTKPYNRDELRTVLR
RAIGIQALAAKAEHAEHALSESEARFRSLVEAATDSIVLADENGRILSWNQASARLFGYT
DEEVRGQPLTMLMPQRYRVAHERGLARVKDTGQSRLIGRLVELEGLRKDGSEFPIELSLA
MWKTDVAVFFSGIIRDITQRRKAEEILDRLRRLHEVILTQAGEGIYGLDRNGVTTFVNPT
AAQLLGFDPSELVEQPMHQLLHHSQPDGSFYPADECPIYAALRDGVVHRVSRDVFWRKDG
TALPVEYVSTPIIEKGAVAGAVVVFRDITERLEAERAVEESQERFRQLAEHIREVFWITD
PAKSRVLYISPGYEEVWGNSCESLYAMPGSWMEAIHPDDRLRVRDAAMHRQISGSYNEEY
RILRPDGSMRWIWDRAFPIRDASGTVYRIAGFAEDVTERKRVEAALIESERRYRVLFDDN
PSMYFMVDAAGTVLSVNRFGAERLGYDVQELLGLSVLNIFHPNDRDDVRTNLAACLLEMG
RPRGWEFRKVRKDGSVIWVRETAQAVLNDQQTPVVLIVCEDITAMKEAEIALHDSEEFKN
QILRSSADCIKVLDLEGRLQYMNDAGKTLLHIGDLTGYLNKPWADLWEGDDRNAALAALE
AAKAGEIGKFVGFCPTTDGVPKWWDVQVTPMLDTRGYSRRLLAISRDITDYRRVQDSLRA
SEERLESVIRGSNDGFWDGHVLPDQPWHSPMTPVWWSPRVREMLGYNEQEFPDILDSWTS
RLHPDDREIVFDRLAACLERGQSHYDVDYRLLTKQGEYCWFHARAEVLERDAQGYALRMA
GSLQCITERKQAEAHLRLSEERLRTALTESEVGIWDWDVQSDRLYWSPDVEALFGLNPGS
FPGTYAAYIGLIYALDRGPVLMQIEHSLRDQSTLNIRHRVVRDDHSIHWLAWTGRIHRNT
DGVATRVLGIVHATKGHADT
>NIDE0557_HK_Hybrid|Candidatus Nitrospira defluvii
LNSGVRPEDLAPIGRGVAEDSPPADPVTGARRSNEASTESSDSRMTDLLSKEHSILERPF
MEFRPFGLNDQGEKISDISGVVVQSNVDYMFDYLSRTAGTEAAEQALDELCRLLNARLPD
RTYHVTPDSLRNIWNSYSYEFVCYLREFCEHLSGDPQFHVNVGTDRKVPPLIQILCRPFS
TPQLYKMWPYFGSKYVRGVLEFEVGRVNRRSAVLRMTFTDRALVQFGPYRKRCVDVICLS
CKSSIARVQTQLHGTPAATVRDLSCTANGDPYCEWEFTWTPQVRSSVPLAMWMLVAGGTF
TYLHLRRPDVPTVEALGLAAVPASLLWWMITNHMRQAAKPLQRLIKDQEQVVDARHEELR
EAYLEQQSTAVTLRRKINDLTTLHRAGLLFSSTFDREELLTNVLETIVRELHYDRAMITQ
FDRTRNVSHDFRVRGMPQEVADFLRTQEVPVTDPNSVEGTVFLRGEPVLTNNIHEIWDRL
HPFDQKLIAMVNVKSFITVPLKTQDAVIGSLSVDRTHNQALTQDDLDVLVTLASQVAIAL
DNAQAYREIESLNAGLEARVRERTAELEAANAQLKQMDRLKSKFLAHVSHELRTPLTSIV
GFADNMLEGLVGSLNMKQEQYLTRIKANGTRLARMITDLLDLSRVEAGKLVLSFEQVCLP
TLVSDVVEQLLPLAITKHLNIELQSPDPELLVWADQDRLSQILTNLLDNAIKYTPDGGQV
AVELSVDTHDMARIVIRDNGQGIPSDALPKLFDPFFRVQQEERSQTKGLGLGLAIVKDLV
DLHGGSITVRSEVDQGTEFTFTLPLHSREPSPAGQVPAVRRTVLVVDDDPDICDLLRDRL
EAEGVHVCTAADGRAALRMLAETTVDGVLLDIALPELDGFEVLRQLRPTHPTLPVVMMTA
VEALDRAMAAVESGAQDYLLKPFDGARLRQIVDRWFITGSGQSQSSIGR
>NIDE0578_HK_Classic|Candidatus Nitrospira defluvii
MATHAPPSDEIDRVAALSRYRILDTPPDIAFDDLAHLAAALCRAPIAAITFIDQDRQWFK
AKVGLTMTQTVRSSGLCAQVVQHKTLIAIEDARADPRFSSHPLVREDPRVRFYCGAPILN
PDGHAVGTIAVMDAAPRVPTEEQCQALRRLARQAAAQLELRRLTFDRSPLDAQSLEEIMA
GMADAVFATDRNGRVLGANHEAEVLLGRTSSDLTGRLLHDCVHRHECGAAQGSGELCGLV
SAAALRGRTGSPNDVFVRNNGSTVQVSWIAAPLIRGGEWVGGLVSVRDLTAQKRNEEALG
VLAGTTRATGVAFLRELVETLACSIGAEYAFCIRPLPGQVRAKAVAGHGPDGSLEQVEYD
LAGTPCEHVLREGFCHYPDAVQAAFPQDEMLRQLSIESYMAVTLPSPTGEAIGWIAVLAR
TPLKDPEWAESLLRMAAGRAGSELGRSLAEQQLQESEERYALALRGTSDGIWDWNVVTGE
AVHSAGWKALLGFAGDELPDLASSFFDRVHPDDLAHVRAEIRNHFERREPFDVQCRVRHK
DGSYRWIQSRAQALWDEEGRPYRMVGATTDITGRKQTEEALQLAKYTVDHATEAIYWVGS
DAELLDVNDAATVMLGYSREEFLGMTVPDLNPSFPAETWPGYWQETREKGSVSFETSHRT
KDGRLIPIEVNANFMYYNGRECHCAFVRDVTERKRAEGALRASEERFHLAIEATNEGLWD
WNVRTDAVYFSPQWIRLLGYRPEEVTGGTVFFFEILHPEDAPRMREVLQAHLDGRTPTKE
LEVRLRHQSGEYRWYLDRGTVVARDPSGQPLRMVGTITDITERKQAERERAEALSTLQTI
METVPDVIFVLDLEGRLSKWNLRLETVTGYTHNELLGKSALEMVPRTEADATSAAIRQAF
EAGYAELEGHLLTKDGRTILYHWNGTPFTDLHGRVVGITGVGRDVTDRKQTEALLRSSEE
RFRLVAQATNDILWDWDLLTGDHWWSPNACDKFGYDPRTEPSVDAWSNRLHPEDKERVLD
LVSQAIQTDVRTFFAEYRFQLADGTYGYFLDRAYIVRNEAGGAMRMIGAMIDVTAPRRAY
ASLEEAYRRFQAMSQELHTVESNERRRLSRELHDEFGQLLTSLKFDLASVKRVAARSSVA
GGRSPERLARALETTDLLFARLRQIVRVLRPPVLEELGLEAGLEALIADVRARTGLCCSL
VFEQAHRRGERLPTLETAFYRIVQELLTNVIRHAHAATVSILVQRNRREWRLTVTDDGVG
FDVGVLSPLGGFGLRGIRERAEILAGQVEISSGVDTGTMVQVRIPVSSTSGRSTEGSVPP
GPASRRRKPVHE
>NIDE0579_RR_NarL|Candidatus Nitrospira defluvii
MNKCRCLITDDHPIVRRGVRELLEEEQLCSEISEVRTGEEALEAVRRQPWDLMILDIALP
DKHGLEVLKETKLLQPSLPVLMLSLYPEKEFAMRAIKAGASGYLTKQSAPSELLAAVLRV
LQGGRYITAALAEQMASVIETGVDGSLHARLSDRELQVLRLLGQGKSVSVIAEELRLSVK
TISTYRARILEKLSCESTGELIRYAIEARLID
>NIDE0580_RR_NarL|Candidatus Nitrospira defluvii
MDAQHLYRIVLIDDSRMARLGLREQLNRTAEFRLVGEAASMTEGLELIEKLNPDLVLLDI
SLPDGSGVHACSRLVAGRPDTRVLILSVYDDPAVIREAIAAGAQGYVLKDTPVAMWRNAM
RRAAGSGVVLGPQLIGLVLMEVREMANGLTTACMGDLSPQERRLLPLVAEGRTNKEIAVA
LSLSDKTVKNYISNMYSKLGVTRRSQVATLYARTLPSGGILAEDCA
>NIDE0581_RR_CheY|Candidatus Nitrospira defluvii
VALILVADDDEKVCRWLRTVLELEGYRVIEAADGRQALRTIQRLSPDLVMLDVYLPVQDG
LDTVLRVHNRQMPVKVLAISGHAVQGYDILKIAAIFGAHGTLENPFSVDRLLLGVRVLIG
PAHPHVA
>NIDE0584_HK_Hybrid|Candidatus Nitrospira defluvii
MSVHQRRAKHRRDHRLDPSIINVLPANIAVLDAQGTILAVNESWERFAAANGFTGESYGV
GLNYLRICDAAGTQPDAQHVAQGIRHILDGTIRAFSYEYESSSSTLRRWFRVIVTPMQGS
RSYGAVVMHINVSDLKQAEAAMHQSEVRLRAIVDTAVDGIVVINERGIIESVNPAVTRMF
GYTSNQLLGQNVKLLMPDPYHTEHDRYLTNYLQSGQKKVIGIGREVLGLRNDGVSFPIEL
AVSEMLVDGARKFTGIVRDISLRKQAEAQFRQVVESAPNGMLMIDSLGNITLVNKQVETM
FGYSREEMLGRPVEMLIPERFRPNHPAHRIGYFSAPSSRAMGAGRELFGLHKSGQEFPVE
LGLNPIDTPNGKLALASIVDITMRKRTESALSKAAQDLEWKNWEISEARDQAVKAGQAKT
DFLATMSHEIRTPMNGVLGMTTLLLDTALSTEQRDYLQTLRHSSESLLRIINDILDFSKI
EAGKFTIEQIPFDLRMTIEDTLDMLAPASQDRHLELVGLIDAQTPRTVIGDPGRIRQVLT
NLLGNAIKFTEQGEVLIQVLPLDEDPTFVMLRFEVIDTGIGLSPEAQAKMFQAFTQADSS
TARKYGGTGLGLTICKRLVELMGGEIGLQSMPGLGTRIWFTVRFALQADAAPPVMPPLTS
NDFAGRRVCLVDDNPTNRSLLQYHVSGWNMHHESAVDAPSALALLRQAAADGTPFDLAII
DIHMPDIGGLQLCRLIKEDPAIRATHLIVLTAFGQRGDSIAAKEAGASAYLPKPVRERQL
ADCIRLILGRKDSDETSTPLITRHTMSEAQAQAAQRLLVVDDNPVNQKVALKMLEKLGYR
VDVAGNGMEALAAVCRHQYPLVFMDCQMPELDGLETTRLIRSQEQAGTHLPIIAMTANAM
AGDRENCLKAGMDDFISKPIVPDQLREILSRWLPSARLTPPQKSFAPSDAGNAA
>NIDE0585_HK_Hybrid|Candidatus Nitrospira defluvii
MHHLRSFQLRDMTACGAALRRLGTDAASLEQVADRLVRHLYKSLTMGHLGEPACSLVRLF
KTTPYSRLTPDLRALADTRIGNTPPAPSLTCLTLLASAGAVPGWNDPAHSSRFRVIPLDT
LEAVERLPMFSQLFRQLGVSLPSLTQPGPSVLLDQHEQSFNVFHIPEAEGSPYVPGQEEF
VRTYGIRSVLGFGAPLPDGELFSIILFSKDFIPESTATLFKPLALCAQIALAPYATTTAA
SHPHQTSRPEQAGDDPTPVHNAHLQARIADLERLLAVHEQTVDEQADRMDLIVQGSQMGT
WDWEIPTGRVTFNERWASTLGYRLDELEPHVRTWEQLVHPDDLQQVMATVSAHLRGDTPT
YSSEHRLRRKSGAWCWVFDSGRVVKRDAKGAPLRAAGIHLDISDRKALEAAQARAQCDLH
AKQQALDEAQTQAHLGSWHWNIETGQEAWSDEQCRIFGHTPDQSLPTYATFLSALHPDDV
ERVKQAVDGALTYDSPYNVDCRIRRPDGEVRHINCRGVVQRDPDGRPVSMAGTVLDITDY
KRTEFAWRDSETRMRSIFESAIEGIVVIDERGRIESANTALLNLLGYQAHELIGQNISLL
MPSPYREHHDEYLANYLATGKRTIIGSGRDVPAVRKDGTQIDLHVSVSEMQIGTEKKYTG
MLRDISERKRMEATLRESEERFRQLAEHIDAVFWLTSPDKSEVLYVSPAFETIWEFPRDL
LYVNPSFWLDHIHPEDRTRVATAAACQMHLPYDEEYRIVTPSGQVRWIRDRSFAIKNAQG
EPYRIAGITVDITAAKQMEAQIRASELRHRALVELSPHAIFVNCEDRIVFTNQACVKLLG
AIAPSQLFGKTVLEFIHPESQAKVQQRIATIRETNQPVPPTEERFVGLAGAIIDVEVAAT
PIMFEGKPAIQVIATDIRARKDLERALLATNLQLQTILASATNVSIVATNTEGTITTFNT
GAEELLGYTSDEMIGQQSLILLHVPEEIDRHAKELSDLYERPIQGVAALVEHANRGGFDE
REWTYQRKDGSRLTVLVTITALRDSDGVVTGFLAMGKDITSRKAAEHALAEARDEALRAA
QVKADFLATMSHEIRTPMNAIIGMTGLLLDTALTKEQHEFADSVRRSSDGLLTLLNDILD
FSKIEAGKLHFEQLPFDLRMTVEDTVELLAEQAQSKGLELIGLVDAAVPTAVVGDPGRLR
QILVNLVGNAIKFTAAGEVFLHVTRETQGGLDLLRFTIKDTGIGIPEAVQGRLFHAFVQA
DSSTTRRFGGTGLGLAICQRLVSQMHGQIGVESHSGQGSTFWFTAQFPETTLATAPSPFS
WSRLRGRRILLVDHCDTVRQAMRQELTSHGMNCTVAQSGPEAVELARTAAASQNPFDLAL
IELHLSDMDGFETAALLKQGPATAGIRLIILTTVGRRGDGQTARSIGIDAYLTKPLRQAQ
LLECLCLLLAPESTAGTPPNAEPPALITRHTLSESQAGPKPRLLLAEDNPVNQKVACKML
EKLGYRVDVAGNGQEAVAAHERSRYPLILMDCQMPEVDGFEATALIRKMEGRSAHTPIVA
MTANAMQGDRERCLAAGMDDYIAKPVRPKELQAILDTWLGTAGAATGTNG
>NIDE0586_RR_NarL|Candidatus Nitrospira defluvii
MNEIQNTPARVFIINPQELVRVGMRTLLNSVPDFMVIGEASSKEEALPLVLHHTPDIVVL
DLRVQDGTGIETAKEILAHLPETRVLFLADALTDSTLLSAVATGAHGYVLQEAGAETLLH
AMRSLTKGQSYLDPGVTRHTFAYLRKVADREPERGRHLLSPQERRLLPLIAQGKTNKEIA
AELGLSDKTVKNYLANVYSKLHLSRRSQAAAFYLKTIP
>NIDE0686_HK_Hybrid|Candidatus Nitrospira defluvii
VQIERSFLSSRVARRVFFLFILCALLPVGALSLVSFSDVTGQLTQQAERRVRQESKVVGM
AIYQRLLFLESKLLSLIVQGHPSSSPGPLGSQQEAMPNTPLFLGLAQVIKGGAVQVLFGE
NHVLPALSPTQWSLLRDNKTHLITANNRAGSRRVFLVRAVSSGMPEEQAVIAEINGEYIW
GLVRQVALPTDLAMCVFASATEILFCSESAPAQLPGQWSRHEGNDNPSVYEWSDGQDSYI
AGYWAIPLRYQFSTAPWTVLLSESRRSVLAPLASFHYRFSLVVVIALLCVALLSVNQIRK
TMVPLEELGEGTRRIAKRNFATPVQVKSGDEFEELAASFNAMACRLNQQFTQLATIHEID
RSVLSVLDPSRIVNTVLARLREVSPCQGLAVLLIDPSERTRGWLYARLGPESQQTTMQGV
TVTEAESRMLTAHRDGSTLVQPSGAGAFAALRGRGNESLLVLPLFRSHDLLGGIVLSYRQ
APDMHEDHIMQLRQLADQVAVALSNASDLAERKRAESSLRESHTQLEAAMAELKTTQQQM
VQQERLRALGQMASGIAHDFNNTLSPIMGFSELLLIAPQMASDPAQLKEYLQTINMAAKD
AAKVVSRLRDFYRPRLDADLAGIVDLNSLVQQSVKLSQPKWKDQALANGVAIEIKTELEP
VPSVAGHESELREVLTNLVFNAVDAMPKSGSITLRTKVDGDAVRLEVSDTGTGMTEEVRQ
RCLEPFFSTKGEKGSGLGLAMVYGIIRRLRGTIDITSAVGVGTTFSIRLPIQTEAETGTE
HDGHNMDGVRLQVLVVDDDPLVGRVTGEYLRVAGHSVEVVGSAAEAIKRFNPERVHLVVT
DHGMPHMTGRQLAGVIKKVSPDTPVLLLTGGDQIEPEDTVSQAVDAELSKPLTMGALRQA
LSTLRYPKSIPAESQKEIGDAA
>NIDE0687_RR_RpfG|Candidatus Nitrospira defluvii
MSDLDVSAVKLLLIDDELPSLKLMEAILKQAGYEKITTTTDPRQAVPFYQEVKPDLIATD
MRMPHMDGFEVLRQLTAVIPAEDYVPILVITGELDAPTKHRALAEGAKDFLNKPVDATEV
VLRIKNQLVTRQLHRQLHMHNEHLEAQVRLRTKIVEQTQLDLLNRLALAAEYRHDATGGH
AWRVGRMAMLLAEIKGLPADQVDMIKKTAPLHDIGKVGLRDSVILKDGPYVTADWEAMKQ
HTKIGSRLLSDSRAPLLMMAREIALTHHERWDGTGYHGIKDVQIPLAARIVALADAFDIM
THPCSYKPTMTLSEAKIEIHMQAGKQFDPDLSALFIQLIDREGEKLLAATGPLQLVA
>NIDE0694_HK_Classic|Candidatus Nitrospira defluvii
MSPPAESEKKAAAETHLHRTLTSVVNGLPADAALVAIFHQEQGPLTTQVHRGFTPRDVQS
IVRTLSSQKVLTSVPAGNDPEASRTMRLRLVTPGAKSLLGVPLRHRQRTFGFLVIGRKDN
AVYAKKDKTMLEQAGDDITKALERDSLFDLNVLLSRPLVVQEPQPVIATPDVYNAPTSHA
TPEIQEKIVLLLNELGQTLAFDRAWIGAYDPLAGNVEVLGIAGEQKTDPKDQKKDLKAGQ
RLTLDASAAGWVVRHRKPRVDHDLASTQGRFLDHKHLYKDRFQSSLVLPFFLRGQVGGTI
TLASKEADRFAVTDARLLEPINLKLVDLLQAAPPAAAGTAKAEGAPDTAAGSPALISAEP
VIRKQERQAAIGEFSAFLATEIREPLGSIRAQLEEVTAEGILDFDPQTRVENAMRDLIRI
EAILNEILDFAKPLDLMRRLCRVPEMVENALTVVATELEATRIQVVKEYAGVLAPVRADE
AKMQQVFLSIFKNAIEAMTPGGILTISMSNQRAGRHLEVQILIKNNGAPIPPEHVDKVFE
PFFTTKRSGTGLGLATVKKIVEEHQGSIGISGTPGEGTTVTIRLPGVSRGPAHRYRGRGR
RPPRRPTAAS
>NIDE0778_HK_Classic|Candidatus Nitrospira defluvii
MVDTGHASHIHQGNAPPMLSSTLPPQAAGVGPSLNSNSLKSPLADPPHVSPGERSMPEIK
TRLHWLMGLRVVVVTVMLGLSLAFQSTRGESAPAFTALIIFTYTITIAYALVLRRLASPA
AHTVFTWVQVGVDIVLETVLIVRTGGVESPFAVLYVITVTVASLVPHRRVGIVTGAGCTL
LFGGITVVQYFGLLNAAGWLPPSKLEGPEVLQTFEVYGLAFLVVGFLSGALADKLHHADQ
SLREKEQGLSRLQVFHESIVRSISSGVFTTDEEGRITSFNPAAHEVTGYAFAAVQGRLWR
DVFNWHPGTPSEEAALTSLSPLRFEVECSHANGSRLVLGMTVSPLQEQGTQRGLVCVFKD
LTQIRYLEEEMRRRAWLANLGEMSAGMAHEIRNPLGALAGAMQMLRQDVGSDDTSQRLMD
IAIREARRLDNIITEFLQYARPPALNLAEHDLNKVLADTLDLIQHEARSRTGITIVSRMA
PNQLMAQVDQDQLKQVFWNLATNAFDAMSAGGTLTIATGSRQVEVGGRRSDVIEIAFQDN
GEGIPKQNFDKIFLPFFTTKKEGSGLGLAQVHRIVELHEGWIKVESEIGHGARFVVCLPQ
SAETGVRLRDEGREPWKRF
>NIDE0779_RR_NtrC|Candidatus Nitrospira defluvii
VEKILVVDDEQGLRDVLSIMLKRAGYVVTVASDGDEAIAQVQKEIFDLVITDLKMPRVGG
LEVLKAVKAASPDTVVLMITAFASADSAVEAMKHGAYDYLTKPFQVDEVQLIIRNAIERR
RLSTENMLLKRELASQSSFSQIIGQSEAMQKVYDVIKKVADSKSNVLIGGESGTGKELVA
RAIHFNSARASMPFVTVNCSAVPETLLESELFGHMKGSFTGAISNKAGLFEVANGGTIFL
DEIGDTTPAIQVKLLRVIQEREFRRVGGTQDVKVDVRIVAATNRDLEKAVAEGAFREDLY
YRLDVIPIKLPPLRMRTGDIPLLSQHFLEKFAKESGKPVPTMSQEAMRVLLAHEWRGNVR
ELENVVERVVAFTTGSSVTDADIRGWLHKPVSNHQALPSELPEDGLDLEGLINTIEKDLL
LKALERSQWVKKRAARLLRLNTRSFRYRLEKYEIKGGRD
>NIDE0804_HK_Hybrid|Candidatus Nitrospira defluvii
MNPLIPGRAPYALITDDDIIIRMFAREALEQAGWVVEEAQNGSEACELFQKCPPDVVLLD
VMMPGMDGFATCAALRRLPGGEHTPILIMTGLDDFESITKAYDAGATDFIVKPLNAMLLT
HRIRYMVRADQVLQELRESQATLTQARDAAIEGARLKSEFLATMSHEIRTPMNGVLGMTD
WLLDTPLTAEQLDCAQTIRSSGDALLVIINDILDFSKIESGKLSLELLDFDLSTFLDRVM
ALFGERAQRKGLLLTSRIAEDVPGSLCGDPARLQQILSNLLANAIKFSEHGSVSVLVELD
QRPAEQGLEFPATRYGEPSAQQEQVTHIRFSVSDNGIGIEPSAFSKLFQPFVQADGSTTR
KYGGTGLGLAICKQLVELMGGHIGAESEPGSGSIFRFTVPLQQPLANSNRRREAA
>NIDE0805_HK_Unorthodox|Candidatus Nitrospira defluvii
MHPLLKRQLKRIGLEAATVPPSLDSWQQLLERVSQSYLESDQGHELLERSIALSSLEMQE
LNEQLRRTSESQLAGERDKLQTVLRSIGDGLCVVDGHWNIVLLNPEGERLWGLTEKEVVG
RRLHDMISLSYGTKLTEPIFTQILLDDTAQGGSFRTDDGLLTSITGRSFPVSCVLAPIVQ
ENRSAGAVLVFRDIMERKQTEDIRRHTESLLRRQQTTLLELTRNSIIQSGVLEPALQEIT
RATAITLGVSRTSIWLLSEDHDSIRCKDLYESSKHSHSSGIDIQSAHFPEYFRALLSERV
IDAADAKSDPRTREFTASYLEPLGIGAMLDIPIRFKGKLVGVLCNEHIGPPRPWMLEEQQ
FGHAIASLVSLALEAVERLHAEGALRKSEGRTRLIIDTALSAVIGMDERGLIIGWNTQAE
QIFGWTRQEALGRAMTDTLIPPAHRETHQRGLERFLKTGDGPILNKRIEVTALRRDGTEF
PVELAITPLRIENAYTFTAFVVDISERKEAEEALRTSEARLTMTVQGSHIGIWDWNLTTG
AIYFSSQWKNQLGYDDTTLPNSFDEWRTRIHPDDQPFVQETIQACLDGQRSQFELEHRLR
HRDGSYRWILSRGSLIRDLYGVTARMVGIHIDTTDRKRTEEELRSAKEAAEAASKAKSEF
LANMSHEIRTPMNGVLGTTELLLNSALTDKQRHLASTVHRSGRTLLAIINDILDFSKIEA
GKLDLECVDFDLLPVLEESLELFGEAARRKQLRLSQHIADAVPRYLKGDPVRFRQILMNL
LSNAMKFTETGGVSLSAEYVEGTTTQALLRFAVTDTGIGIPPAAKSRIFDAFSQADGSTT
RRYGGTGLGLSIAKQLVGLMGGTITVESTPGSGSTFAFTTRFDLQPLGSGLSTKLAPYTQ
WADPLVSPGQTSDIPSPQVTEAGAAASSPKQSGRILLAEDSPVNREVAVGMLEQLGYEVE
VAENGRQALAAAERDHFDIVLMDCQMPEMDGLTATGEIRRRETASGRRRLPIIALTAHAM
QGDREHCLTAGMDDYLSKPFTQMQLQGIVRKWLSHHEPPSQAAQPNTTAPGNQSVPPQPT
TEPAADTRSASPGMDFKALDGIRALQRPNRPDVLASVLRKYLDNSRESVDALRDAIRAND
PIALEAIAHRLKSSSAQLGAIAVAACCKELESMGNRKNLVDADQMFAQLESDYRAACTVF
RNEIAKEKQA
>NIDE0807_HK_Classic|Candidatus Nitrospira defluvii
MDLLAGLPKGEALAEPAWNARHRGILSILWLHVPGVPMFGIYMGASPALYLGGGGLLAFI
AVTARLSVVRRRLQSAIATCGLMTASALLVHLAGGQTELHFHFFVMMSVIVLYQDWLPFL
VGLQFIILDHGVVGTLMPDMVYGHTDGQTHPWTWALIHGGFILAQCAALLYFWRVNELAQ
DEVRESEARTRMIIETALDAVITTDATGTINGWNTQAELMFDVPRTEAIGKPLTTYVSAA
CPASGSTPITPYAGLVPGAILNRRSEMLGLTYQGTSFPVEIAMSCLAAGGTQQFTIFVQD
ISERKQQEERLCRAKEAAEAASLAKSQFLANMSHEIRTPMNGVLGMTELLLTTPLNDTQR
RYAHTVHNSGTNLLHIINDILDFSKIEAGRLVLEYIPFGLRQLLTETIGLYHEQARKKGL
ALSVTMTPDIPDMAHGDPHRLRQILTNLVGNALKFTETGTVAVFVRPDEGRPGRVRIEVT
DTGIGIPLQAQEKIFDSFSQADGSMTRKYGGTGLGLAIVKQLVGMMGGQLGLTSTPGQGT
TFWFTISVDRSASPETESQPHRSDETPLTMATRQQPDI
>NIDE0815_HK_Unorthodox|Candidatus Nitrospira defluvii
MRRFLQQLRQSVRRATRQPATDSGHSQTERRELPPSNTTTSLDEGRALDAILCSLDEGLC
IVDAQWHILRLNPQAEILFGAPAHDLKGRPAYQLIAPGPEEFRHECLVTDSSIPPLQSGL
PYRTDNGFLLRQDGQLTPISLTITPMSHDGVVSGAVLTFRDLTTQKEAESHQVENSALLR
RLQTGMVGLASNQAIYRGQLTEAFHLITRVTAQSLRVARVGIWFFAPDHAVLRCADLYDQ
PGDQHSNGIEQPAALYPQYFSSLEAGEMIVADEAQSDPRTVEFAAHHLLPLGITSMLHVP
IRAEGILVGALHCEHIGTPRVWTTEEQQFAASVANTVSLAAEAADRHKAETETKRAEQFL
DSVIENLPIMVYVKEAEQLRFTRWNRAAEELTGFSRDLILGRTGHDFFRKEEADRFTLHD
REALRSGRLIEVASEEIHTQHRGVRLLRTKKLPVMDEQGRPRFLLGIAEDITDRSAHESI
LHESEEKYRELFESSRDAIMILASPNWNFTACNPATVQLFGARDAEHFTSLGPWDVSPEH
QPDGEESMVKAPKMIGMALQEGSHSFEWLHKRVGGPAFLASVQLTRITLKGTTGLQATVR
DITEQRRSEATLQAYSTFQKAMLDNAGHAIISCKPDGMIQVFNPAAEALLGYSADELVGK
QTPGIFHDLDEVVARARQFSAELGTTIEPGFDVFVEKCRRNLPNEHEWAYVCKDGTRKTV
LLNVTALREADGRITGYLGIATDITPLKLTAQELVSAKEAAEAANVAKSRFLANMSHEIR
TPLNGVLGMTELLLSTSLSAKQQSLLETVRRSGVALLEVINDILDFSKIEAGKLELEQVE
FGLRQVVEEAVELFAGSAGNKKLELTYFIPADVPDSLVGDAVRLRQILLNLIGNAIKFTA
QGEVTVAFALAEQHADTLTLACRVRDTGIGIPDAAQAQLFTAFTQADGSTTRRFGGTGLG
LAIVKQLVQLMGGEVGLVSAPGQGTTFSFTFTVTRGSAHAAYPPLAERHLAGRQILIVDD
MRTNLEILATHLQSWGATVFTAESADDALLQLEHFRHKQQQIDMAILDLRMPGRDGVDLA
RSIKEQAAYQNLPLIALSSVERLSDESDVTHRLFHSFLRKPVRQSLLRDCLTRALGGSAG
PVPHSPEFAATPRPRVDARILLAEDNPVNQDVASSMLEMLGCRITIAPNGRAAVEAATTG
RFDLILMDCQMPEMDGFTATAAIRRQEATATDRRHVPIIALTANAMEGDRARCLAAGMDD
YLTKPFTVAQLYAFLTQWLTPRPAEESETDQAPSTHAANTHEPAATEEAPVPTTIDKAAW
DAILSLQRPGRPDILARVLATYLDDSRQLVEQIRSAVQSQDSVALSQAAHRLKSSSAQLG
ILATAAHCKELEALGRRARIDEAAHRLSQLIEAHQFACAAITSELQQRSAR
>NIDE0816_HK_Unorthodox|Candidatus Nitrospira defluvii
MAVLITIGMAGFATFRLIEIRQSIEQATQARALAVSRTFSMVGAAAVLDNLFRIQEAFGR
YAQDSDILSILIIDPDNMIVAATNPRQIGQQLTDETLAQAHETNAETISHGQTVDGVPTL
LVATPLLNEQDIAAWVRIEFSLAAMQEELTREARHLFLLSVLFMGATISVAQLGIRRMSG
LFRETAEKLQKTLHTLHCVSEQAPSGDAASDHDNSHASPSCKGDLEQVVDLVETTTTLLT
TQAQRLQSFTDSLEQAVRERTTELHQAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMT
ELLLSTALTQKQRSLTETLHRSGTGLMDIINEILDFSKIEAGKLKLERIEFGLRQTVEDA
VDLFAETAGRKHLELTCFVPPDIPDTVIGDPVRLRQILLNLVGNAIKFTQSGDVAVTLEL
VTPTTTNLTLKFRIRDTGVGIPEATQARLFQAFSQADNSTTRKFGGTGLGLAIVKQLALL
MGGDVGVDSVSGQGSTFWFTVELEQAAQRTAASGATERPLDGFSILIVDDNPTNRHILET
HLSAWGAAVLSATSGLEALALLDRQCTAQRRIHLAVLDIHMPDMDGMTLAQTIREDARLS
GMVLVALSSVDQVTDESQRHPSLFSAWLRKPAHQSLLKDCLTRLCHHVPTTGAPAPVQPD
DQAVPFAAHVLLAEDNPVNREVAFTMLELLGCTTTMVENGREAVEALTNRSFDLVLMDCH
MPEMDGLTATALIREQETQATQPRHTTIVALTANALQGDRERCLAAGMDDYLSKPFTLTT
LKEVLHRRLSITGPSRTTAPPLRSTPQTPPRQATLPPEPVLPGDDHVDLKAWHAIRARQR
PGQPDLLHKALSLYVPHADAQLTQLQQAMAGADMQAVKTIAHMMKSSTAQLGAPRLADLY
AQIEAACRAGTPDNLPDLCGRLIPEHRAVCALMSEELNRAGRSAA
>NIDE0857_HK_Classic|Candidatus Nitrospira defluvii
MNLGIRWKVALGTLAAVFVGLAVAGWLVIRSVEQTELSRMAETLETSSGLAAMTLRPLFD
QSGSTVPGSLLHATVRDLSQQAHLRITVIRQDGTVVADSAVPTEGLAHVENHLSRPEVAQ
ALRSGRGMDIRASQTTGERTYYVARLLSASTPAQPSIPVIRLGLPLTSIDERVRHIQQDL
ATAFGAAFLLAMTLSLWVSRNLTKPLSEMAAAARQLAGGTPGVRLVVSSTDEVGLLAQTL
NEMTDQLETKIKEVSDDRAQLLAMLIAMVEGVMVLDYRGTVVQVNPALERMFSLELTESR
GRHYAELIRHEGLTALVSSVLQTRSGQGGEITLSPSGRCLRVEASIAGGSREQEACAVFV
FHDITELRRLEKIRKDFVANVSHELRTPLTSIKGYVEALLDGGKDEPATATAFLEIIMRQ
SNRLNLILDDLLQLSQIESGQVLFRREPVDLRALLERTVAVIKPLADKKHHTIELSLPDE
YWVVEGDEERLVQVFINLLENAVKYTPDQGRISMAIRNATHMRAATPRPMIEIVVADSGI
GIPEADRPRVFERFYRVDKARSRELGGTGLGLAIVKHIVEAHSGQVWVEGNTPRGSRFVV
HLPVAQDSSTAVSTETGSR
>NIDE0858_RR_OmpR|Candidatus Nitrospira defluvii
MPPSSTTHKKILIVEDEKDILQLVKLYLEKEGFRTVSAMTGTEGLRQVKAEHPDLIILDL
MLPELDGLEVCKRIRLNQETALLPILMLTAKAEESDTVIGLELGADDYVTKPFSPKALVA
RVKALLRRLERNANSPQTQYHYGPLTVDLSRHEVRLDGQEVALTAKEFGLLEHLLRNIGR
VLTRDVLLSAVWGYDYYGTTRTVDVHVRRLKQKLPLLDDAIISIKSLGYKLRESDVPA
>NIDE0934_PP_HisKa|Candidatus Nitrospira defluvii
MDSESMKAALTELEHLEMASTTILSEANDRLRVLSHSLQEAGEFERGALVRDLHAEIRHT
LPLITLRLYELGKQPERPDAPPHAQQVADSFHILDRTLRQLRALASDVQGHNA
>NIDE0935_RR_NarL|Candidatus Nitrospira defluvii
MNNIRVLLVEDHTLVRAGFRVLLEKIEGILVIGEVSDGRSATKLAKELDPDVVLMDIAMA
GMNGLEATRRIRQESPRTKILMLSMYTNEEYLKEALRAGAAGYLLKDADRNELELAIKAV
WRSETYLTPSMTKFAVDAYCQQGEAQTGPLARLTGRQREILQLIAEGCSTKQIAQRLDLS
VKTVETHRAQLMERLDIHDVPGLVRLAIRTGLVQSD
>NIDE0936_HK_Classic|Candidatus Nitrospira defluvii
VGALPLAALHDPSELQQRAAACTSKPATGTTDIFQIIVANAEPGHTTEHDWTYLHRNGHT
LPVHLSISAFPNGSGQIAGYVLVLQEIRKEIRSNDVLQHHAKLLDLANDAILVRDLERDT
IDYWNDGAVRLYGWTSKEAAGAYIHDFLKTTFPQPLADIKKTFLAKGYWAGELLHTTRHG
RRITVSSRWTLLKNSDGAASASLELNTDITEQKRAQEALTAAHEELEHRVAERTAALSDA
NSRLRILSRRLMEIQELERRAIARDLHDEIGQALTAIKMNLRELGEQRDGSTAAADGKPL
SDSLQILDQVLRHIRNLALDLRPSMLDELGLVPALRWYIGRQAERAGWKVQFLADEVMTR
PSPEVEISCFRLTQEALTNVARHAKATVVEVRLEMGRRQLDLIIRDNGIGFDSNLIRTGA
RAGTSVGLSGMEERVRLAGGHMVIQSAPSTGTEIRATFPIGPESAETEHE
>NIDE0964_HK_Classic|Candidatus Nitrospira defluvii
MKVLAFSALVNALAATGLGMFVYFRDPAAARNRIYGLYCLSIAFWSVFYCGWQLTESKDL
ALSLLRLVMAGASLIPILYFHHTVTFLDITARHAKALKIGYGLAALFLLADTTPWFVAGV
HPAMSFSFWPVPGLFFHPFLLYFLWYVVYATSLVGVALRDANGIRRHQYAYMLAASIIGY
AGGATNFPLWYGVPLLPYGTVLITMYTALMAYTIVRYRLMNISVVLNKGLGYAIVLAIIV
VATSIGAVLSNRATGHSTPPLLAGTLFLICALWVLSNNPRSTSNTIFSAVCGAACLWLFG
CFMLFSASREDEALFWVQVIYTGVVFLPALTYHFAQSLSGGAAHDRLIVWNYAVGALFWS
LLFTPYLVDGQYVYYWGRYPKAGVLHPWLVAYVVAGGGVTVYRLYQGYRLHLSSSPLLGA
QLKYTVVALALGFLASLDFLQNYGVGFYPVGYLLAGLSVTVVAYAIARYELMDVSFVPSR
PKVMLSIKLMGLIPAYMMILLVIRIFTGTFHYLLAGVLFGLFVIVSSGLANLQKGVERAI
GQTLFRERYDAYDTLVQFSKSLVAILELKSLTKEIVQTLARVMNIKTASVYVLDKEQGIY
SLTASYGFVTREAVVPPIKMEGEFPKTLLRTETALVREEIEYDKADTEHLRLLDTLKALG
SEVCIPLISKDRLVGFCNLGRRANHGMYSTEELALLKTLAQHAAIAIDNALLYEDLRRSQ
LLMRRTDRLRSLETMAGGFAHEIRNPLTSIKTFVQLAPERRDDVEFMEQFSQVVCEDVER
IERLVHEILDYARYMTPKLTQESLNDVVSSCLYFIEVKASSKAITIQKELASDLPYVRLD
RQQIKQVLLNLFINAMEAIGGDQGGRLSVRTRKLVKAVNEPWVQIEVEDSGPGIDPQDLD
HIFDPFYTTKHESGEREGTGLGLTIAHQIVQEHGGYVEVASEVGHGTRFMVNLPVNPPIA
EWQAAQPAFDDGRKLAGAFLARPHLGLDEQFGKPPAPIKATP
>NIDE1040_RR_NarL|Candidatus Nitrospira defluvii
MSGTLAMDACQDLPPAKADVRILLADDHALLRRGLREFLRDFLVEDGLTPDIVETTSARH
AIDHIRTGAWDLVILDLNLPDMPGLEVLRILKSLRPALPVLVVSIYAEEHYSARAIRAGA
LGYLTKERGPQELRLAVSRILQGGHYLPSPETEHSLDEGPHRNGSSPDTLPATLSDREIE
VLQWIAQGRRLTEIAEQLNLSIKTVSTYRSRLLIKLGMRTTAELIRYALDQQLV
>NIDE1046_HK_Unorthodox|Candidatus Nitrospira defluvii
MLAAICLVTAGIFVLDAAVPLGHGIWLLYLLPLWLSSRLAPPAAPLRYASVCTVLLAGGL
WLAPPGVDVTAVMFSRAIGTVMIWGAAYLLSQRREAEDALRAANSRLELRVAEQTKNLVS
ANDRLTAQLVEQRRIEAELRESRERFELAAEGADVGVWEWDLQEHTAYYSSRWKSQLGCA
ESEIGGTIADWETRLHPDDRARALATVTLFQEGYTKQYRLDHRLRHHDGSYRWISSLGAG
VFDEQGRMIRMTGIHLDVTARTQAEEARRESEDRYRTLVEQAGDIIYRTDAAGRFIYCNP
TSLRVLGYLPEELLGRHYLEIVLPQCRSQAERFYGRQFVRKTPRTVYEVPVATKDGREVW
LGQHTQLLLEGGVVSGFQVVARDITERKGVEQALRESEERFSKAFHSSPAGMAISRLEDG
RVLDVNEAFVRVSGFSREELIGMSSLDVGIWVNPEDRRHLAEILTRDGFLRHLEKEFRTK
SGEVRHGLFNVEPVCIGRETCVLTLVLDITRRTEAEAALRRSQSVLQAHQHALMRLTKSQ
HIGSGDWQSALEELMQTSALVLAVDRASVWLLDRTGTILDCVELYEQGQARHSRGQRLNV
AEYPRYFAELLQEQVVDAYDVAADSRASELVQPYLGALGIASLLDVPIFFGGRLAGVVCH
ERVGLPREWTREEVQFATSVGNLVALAYEAKQRLEAETALMSAKEAAEFANRAKSDFLAT
MSHEIRTPMNAIVGMADLLSETPLNEDQREYVQIFRDAGSNLLSLINDVLDLSKIEAGHL
DLDLVDFDLNDLVQRAAELVAVRASEKNLELAYQIQPDVPTSLVGDPNRLRQVLLNLLGN
AIKFTDEGEVVLRVERDPQADGPGTILFTVRDTGIGIPTDKLAAIFERFTQVDSSTTRPY
SGTGLGLTISRRLVERMGGKMWVDSELGRGSTFSFTAKFAVHVQPASAVPPAQWEQLASL
RTLIVDDNATNRLIVRETLAGWGIPAAEVPGGEEALFELRRALKAGVPYRLVILDVRMPK
LSGWQIAETIARTPGLAGVSMIMLTSERRAGDQARARECGVVRYLTKPFRRSDLFNGMMA
VIGKVALAESHALLPQPPESTGDMPGLKILLAEDFVDNRRMMEFYFKSTPHRVETAANGQ
LAVEMFQRSSYDLVLMDIQMPVLDGYAATRAIRSWEQAQGRSPVPILALTANALQSEVQR
SLEAGCTAHLTKPIRKARLLEAMQLYFQTSDPVAPPSSDASSESVVLQVSGEFESLMPGF
LEHRRQELVQLADAFDRGDFETIREIGHGLKGAGGTYGLEAISAYGRALETAAGEKDGAC
VRETLHRLTRFLERLQLVYV
>NIDE1047_RR_NtrC|Candidatus Nitrospira defluvii
MRVLLVEDHIDIRRLFEQVIEARGHDVTACADGESAWEAYSRRPYELVLLDWELRGDGMD
GLQVCRTIRSSPGGDRCVIVMITGHDSPESLRTALQAGVNDYLVKPVGVEFLKLRLTIAE
QWVESVRRRFAAEDQAQALQSQLADHGKFHDLIGRSPAMVVLYEEIQKIAAVDATVLIEG
ETGTGKELVARAIHLSSRRAPHTFLAVNCAGFTDSILGSQLFGHKKGAFTGAIDNQEGVF
EAAQGGTIFLDEIGDISPAVQTSLLRVLQEREVTRLGESKPRKVDVRVVVATHHNLAEDV
EKGTFRRDLLYRIKVARVQLAPLRERPTDIPLLVHAFLGQFRSVMEKPVLQVSLEALQVL
TRHSWPGNVRELKSAVESALIHCKGTVVRVEDLPPEVRNPEPAATYVPLQRQDERTRMVG
ALQQTGGNRSEAARLLGMSRRTFYRRLAEYDVSALGDGGDAPLQ
>NIDE1109_HK_Classic|Candidatus Nitrospira defluvii
MRQRVSLQSLITLSVLSVGILSGTVGLVYAYWHAKQSLHTTVGITFQEIARQSADKAALL
LAKELEWMQRLSALPEIRLSVEGASSSKQPTLQFEQWREEQHRYFHSLVIVRWDGQLVGG
RQSESARTFYAQQPWWPVVFSAQRAWAGPLAVDENGRGFWEVAVPIGGQGQPVRGALKAV
IGTDRILSSIVGSRIGRTGHMMLLAEDGVVLACSMLAPNLHATLRTQSMHAPADAPAARW
FQLEQDTHGGKQSIIGLARVVLPAQIEQARGWFILMQQDPSETFEPLLALMGKLGAFWVG
AVVFIVWLRWRLARRIVRPFGDLIQRVNVFGGAWPSEPLPSQTPSRPSGIVEIDALAASF
DDLAQRLQQASRVKAQYVRRLEQVNLDLATSEEHYRLLWNHSVDTKILIDPSGTILDINR
RGEVILGRPASTLARRPFTELVTAPERPRLLEQLEAVNRSGADLSGGAMHVPIPTGDRTM
EVDWVPVKKAGRLESIMIQLRDLTEQKALERQVVRSERLASLSQFASMFAHDIRNPLAGI
KKTLEWLGGCPEMGQDPPRRCLEDLRFTTDLLLGMINDMLDVYQENYSGLPLSTSPVSPR
LLMNEVLRLFRSEAEAQEVRFNVQVPSEAVWIMGDGRRLQRVLINLIHNALKYSPARGAI
MIRVQVNGGQVSQGETVDGPDACSTVTIQIQDEGPGIAPEDLPHLFEMFFRKKDGQDYRI
GRGLGLHFCRLVVDAHGGQITAANRPEGGAVFTVALPVRQEQVCPSPS
>NIDE1110_RR_NarL|Candidatus Nitrospira defluvii
MPITIVIAEDQRLFRQSLRLLLEHERDLIVVGEAMDGRQAFDLAVAHKPGIVLMDVDMPR
LDGITATRLIRSCVPESKVLMLSVHDDDARIVAAVQAGACGYILKDADHQEFLRIIRATD
KGEPVRSPFMPDGFAKQAVALVNKQEELSGGGLSLLTDREHEMLACAAAGRSNKEIADQL
CVSLDTVKTHLHHIYQKLRVSGRVEAVLTYLQSR
>NIDE1119_HK_Classic|Candidatus Nitrospira defluvii
MRRLRRTGGLQRKFFVALLIVGIVPGMVALWATYRSSTATLKQAIGEGFQEIARSTSIRL
ATAVDNEIDRAIRLALVPLHVRQPVVLANHQAGTTADKTHHQPSPAHPKSNNPPAVDQDT
TGYLDEWARESRHYVRVTIADRQGQVVASTDPRLPPQQAGEVWWREAIQAAPGASYVSNV
MFDPQVNDMVFHVAVPILDDTRRSTIGVVGLVIRRNLLTQMILPIQIGNTGHAMLLDTQG
TPLICPVLPPTAHLIPSTLMNRLTLDRPLWLVADDDAHGGRDAIVGAAPVQLTHALTPGS
LDGNRWYAFIRQAPEETYAPIYSLLLTVGVIGFGLVIVLSAFGFLVGYRIVTPIVALQRE
AEGLRLTLALPEHGSANRPLTPLLSPGYQTGDEIEDLATSFAAMWGVLEENLRTIRSQQH
ELIRQEKLASVGQLLAALAHDLRNPLGVIRSSAQVVLEGPQEEPIRQEMARYIIDEVDKL
SLRLHDFLRYARQKPPDLKAEPAEAVVRAALRQWEAQGGHERIRIEQQFGNALPSIQVDP
EQVKEALMNLLINAREAMPEGGTLTLTTRAGPGNKVEIEVADTGSGIAPEHLSRIFEPFF
TTKAYGTGLGLTNVKRLVEDNGGTLAVTSSQGMGTTFSLCFHPAS
>NIDE1120_RR_NtrC|Candidatus Nitrospira defluvii
MQAPTLLIVEDEERMRRLFELVLKPAGYQLLLARSGDEALRMIQEHQSFDMIITDLQLGT
VSGMDVLEAARQQLPDVPVLIVTGYGTVKSAVEAMQKGAYDYISKPVDNEELKIVIARAL
QVRQLARDNRILRAGLHEQFGFDRIVSVSKEMELIKRLAREVAQTDATVLITGESGTGKD
LLARAIHLVSPRAQGPMVALNCAGIPEHLLESELFGYEKGAFTDAKKSKPGRFQMADRGT
LFLDEIGELSLTAQAKLLRVLEQHVVEPLGGVRSVAVDIRVIAATNQELPDLIKAGRFRL
DLYYRLNVYQLRMPPLRERPEDIEPILTQFLSQARRERGSRIKGMSAEALAILKQYPWPG
NVRELHNVVEWLTITCKQDEITPEHLPASFKAAPPTHEEKPVATPSLLALGLSVEEVEKA
MLQEALRTTGGNVSEASRLLKITRNTLRYRMAKHNLSLPPG
>NIDE1123_RR_unclassified|Candidatus Nitrospira defluvii
MAQAKILIVDDEVVVAEDIRRQLRALGYLVVGVVASGDEAVRLAGEHQPDLILMDIKLKG
SMDGIDAARTIQSRYGTPVIYLTAFSDEETLERARETLPLAYLIKPFVSSDLRAALELAL
FRQRVSRISEQRGRWLEAVVLSMEDAVVTVDQQGRVTMLNPAAEGLTGWAQPDALGKAVQ
EVMVLLEPESGRPVPSPAIQVLRKGTPAGLGGRPFLLVSRNGHEHRITDSAAMIRDERGN
PSGVVLVFRPVSA
>NIDE1163_HK_Classic|Candidatus Nitrospira defluvii
MVGAAALLACLFFILDLQLPLGVANAVLYSAVVFLSAASQYRWLPIGTAITCSLLTIMAA
PFSPRVPGLPAWFEWGNHLFSLFGIWTPVMFIYQRRRTELLLKEVNERLEQGVDARTADL
AASRLALERSEEQLHTLTGRILTAQEEERRRIAQDLHDDVNQRLALLMLDLQTVDRQIGS
APAEAQEGIRNALKGLEELSDDVRFMAYRFHPSILDDLGLKAALQRLLDDFSSRTGVKAL
FVHQPLDHQLDKTTSTAVYRVIQESLSNIARHAKATRVEVEVTVEDEGLAVVVRDDGRGF
DQLAIDRAEGGLGLLNMRERLLAVQGYCEVESNPGRGTTVSMYVPLARVAT
>NIDE1164_RR_NarL|Candidatus Nitrospira defluvii
MTLPRVLLADDHTLVLEGFRRLLDDQCELVGTVGDGRALLEAIPELKPDIVILDISMPVL
NGIDAARVLKVKFPQVKVVFITMHADPAYVRAAFEAGASAYLLKRCVGEELGQAIRAVRS
GNFYVTPLVTKDVVESMLRGIDGGAPSGPELTTRQREVLQLLAEGHTVKDIAGTLNISPR
TVEFHKGQIMEQLNLHTTVELVKYALAQGLTSQT
>NIDE1165_RR_CheY|Candidatus Nitrospira defluvii
MSRPRVLIGDSSRAMLAFLEILLEPQFEVASSETEAEAIVLTARKISPELVILDFSLSFL
EGLGAARQLYETMPNSKVVFFSSHEDPVYVTAAFEAGARGYLVKHLTVDLGHYLGRVLQG
ERVCCPDGLHTRVARTKDT
>NIDE1222_HK_Classic|Candidatus Nitrospira defluvii
MPESTDMTKLIPPGVLREKVPSTPASIESERRKRHVRPVWIVLILLLPCLALTFYYAQMA
VPVGEESDSFFPSTGYAFVLLLVNLDLIGFVVLTLLLSRNLIKAYFERRHRLVGSGFRAK
LVAAFIGFSLIPTVLLALVASGLVNKAVDVWFNDQIEHVMKDSYEVARMHHAGHVSLAIN
SARAISHEIFREELLLPEQRDLLVAAIARKRAEYATAGIEIFSSKMETLTKSLDPEVPVA
VLDLPIGQLVLQVINGKQELTSVQEAQTGRLVRAGVPIASSIRRGEIDGVVVVDAYVPES
LLGKMESIGRQYTEYKQMKAMKNPIKAGAYLLVAVITVMILFSATWFGFYVARGITVPIQ
RLAEATEAIAQGDLSVRIEAKATDEIGTLVESFNRMTADLQSSKTKVEEANVSLRQSNLE
LDRRRAYIETVVDTIAAGLLSIDRQGIITTFNPSAERMLGLWADRFRGRSANEVFKEYKL
DLFQSVYDRMLVDQRDNIALEGQLDLQGRFLTIGVHCSRMKDESNKDLGFVLIFEDLSEL
IKAQKAAAWREVAQRIAHEIKNPLTPIQLSAQRLRKKFQDKAPDFDRICDESTQVIINEV
GSLKQMLDEFSKFARMPAPHMTVNSLDDVVKEVVALYDSAHREVECVVTLDPDLPLFNFD
REQIKRVLVNLCDNGIHAMNHKGHLWITTRYDTKQRRAVVTVADEGTGIAPEDQEKLFVP
YFSRKKTGTGLGLAIVRRIVTDHDGQIHAGNHQPKGALFTFELPV
>NIDE1223_RR_NtrC|Candidatus Nitrospira defluvii
MSASILIVDDEVSILNSLSSILEDEGYEVSVAKSGIEALKLCAVSPPELMMLDIWMPDMD
GLETLRRLRELVPQTQVMMMSGHGSIETAVKAIKLGAYDYIEKPLSLENVTLRVKHALDQ
HRLEQENRTLRTKVERKFELIGQSPAMRQLKQIIETAGPTNSRVLIGGENGTGKELVARA
IHQHSARATRPFVAVNCAAIPETLIESELFGHERGSFSGATTMKRGQFEQADGGTLFLDE
IADMSLSTQAKVLRALQEQQFTRVGGTKLIKVDVRVLAASNKDLLKEIEKGTFREDLFYR
LNVVPIVVPTLRDRREDIPLLVKHFLHVHAEEQGLKIKQVSPEAMEVFIQYEWPGNIREL
RNLIERLMIMVPGPVIEASHASVALQVRPQLSATQQAAGAQVPHSLLTRHYDSLRDARNA
FEKEFIARKLREHHWNISRTAEDLQIERSHLHRKIKLLDVEMRPES
>NIDE1226_PP_HPt|Candidatus Nitrospira defluvii
MMHHHAEPGSDKIPVRIDSSLEAIIPGFLANRQRDLTTIESCLKQGDLNTIRMLGHRMKG
DGGGYGFDQISVIGDQLERAAMAHNLSALQDHLKGLKDFLARVEIVYIH
>NIDE1227_HK_Hybrid|Candidatus Nitrospira defluvii
MAKRITQTSRTASTSPARLPRTASRPSTALQREQAARLRAERALQRVSKELQRRVEELQR
AKDAADVANRAKSEFLASMSHEIRTPMNAIIGMADLLWETTLTPEQRKYLRIFRRAGASL
LSLINDILDLSKVESGRLDLDSIDFDLSELIDKTSEMLALRANEKGLELVCHLANDVPCH
LIGDPNRLYQILLNLLGNAIKFTEKGSVVMSITNDPELRTPGAIRFSISDTGIGVPHDKI
KTIFETFTQAHSTIARQYGGTGLGLSISQQLAALMGGRIWVESRLGEGSTFHCLVRLGVQ
TAPPPAKVSGTMNLAGLRCLVVDDYPTNRLILRETLFGWGATVVEADSGEQAMEALEVSL
KSDAPFTLLLLDCRMPGMDGFEVIERIHADPRLSSLTIIMLASDRWADDIAKTYDLGLGG
YLVKPIRRSDLQQTISIALGRSKSGFSPSPQGAALQAPPQGRSLRILLVEDSPDNQVLIQ
SYLKNTIHRVDLADNGQIGVAKFQNGHYDLILMDMQMPVMDGLTATRTIRRWEQEQGLPA
VQIIALTALALKEESARIFEAGCNAHMTKPLKRTTLLELLLAYEKTRAQ
>NIDE1228_RR_PleD|Candidatus Nitrospira defluvii
MGILIVDDSTDDRLLIQSILANAGYEETFVAESAAAAFRLLGLDGPRQMAGRVDLILMDI
VMPATNGIEACRQIKAVERYRDIPIIMVTVKTDPVDLQLAFAAGAIDYVAKPISKIELLT
RVRCVLRLVHEIERRRAREQELLEVMRQLQEANQMLLRLSCLDGLTGITNRRQFDDFLDQ
EWRRAARESTPLSLIMLDIDYFKTYNDSHGHQAGDECLRQVAQLISSHVNRPGDLVARYG
GDEFVIVLPGTTVDGAAQVADTLRRKVCEAEMKHPNGDPVTISLGFACTVPSRVAAPTDL
IRAADQALYQAKQEGRNRAKQAGVLTLVHHTHKD
>NIDE1229_RR_unclassified|Candidatus Nitrospira defluvii
MGILIVDDSPDQQLLLKTILKKAGHLDLLIADSATAAYDQLGIDQPEPPQHTPPVDLILM
DFLMPGIDGVAATQRIKSLESLRDIPVIVVTAKTALGDLQAAFAAGAMDYITKPVSSVEL
LARVNSALMLKKEMDCRKTREMELRRSNAELQQALREVKVLKGLVPICASCKKIRNDQGF
WQQLEEYIQQHSEAEFSHGLCTPCIKKHYPGVYPD
>NIDE1255_HK_Classic|Candidatus Nitrospira defluvii
MKSRNQVVLAIAAILFLIVMVMEWMFPLNVVGAFGFVLPILLVATVRSRRLMVVTLALCI
LVTFVGLFQPGKKRERFTAVVFNRIMVACVLTGVAYIGVTWEERKAREEAAKAALATQTE
HLLLANTQLVEIKDKLARSERLAAVGQLVASVAHEVGTPLHSIAWHVEALAEEPGVTPAM
QKRIGIIDEQLNRVVRIIQDLLSSTRQRKPEPTWYPAERLIEPVVALMEPGYHAKGVTLH
TAVASALLVWADAEKIHQVLVNLLSNALAATGAGGHVTVAVTIRQASSEEMEGASCTGRP
DLSTVVTLVVSDSGCGMPREDVERAFQPFFTTKAVGKGTGLGLFLSREAVSAHGGRLTLE
SEIGKGTTVTVVLPGLPSDSAVA
>NIDE1256_RR_NtrC|Candidatus Nitrospira defluvii
MSQAKLFVVDDDEAARTLLAEALAKEGYEVEAFSSGQAAVERGKQSRADVVLTDIRMEQG
DGFLVLKEFKKFSPDTSIVLLTAFGSLEGAIEAIKQGAYDYLAKPFKRDEIRLVVQRSLE
HCRLVRENARFREDARAREPWSQLVGSSPAMLEVYKLVARVSEGRSTVLIEGESGTGKEL
IARAVHLNSLRRDKPFIPVNCGALPDHLLESEMFGYEKGAFTGAVGAKAGLFEAADGGTL
FLDEIGDLGQALQVKLLRVMQEHEVRRVGSTASVKVDVRIIAATNRDLATLVKEGKFRDD
LYYRLNVVRIVLPSLAERREDITMLAHHFLQKYAKQSLHVRGFLPETMALLKRYHWPGNV
RELENAVERAVSLSHGPLLLPEDLPESIRVEPDSGELLKGPPAEGDQDALLTLDEVEKRH
LARVLKETRGNKVKAAKILGIDRRTLYRMAERFGLDFGDEAEEK
>NIDE1261_RR_CheY|Candidatus Nitrospira defluvii
MAPGRKQLSTILIVDDDPSALLVSTKPLRDAGYTVLQAPGSAEALKLYAEHPDPIHLVIA
DVFLPPPGFQLSVDRNPYPRVNGLDMVERLLQDKREIRVLLMSGSPSSELQDRGLVRAGL
PFLKKPFTSETLLSVVREVLAGAPAAPDQKNAPRPGHGDVEWVD
>NIDE1484_RR_NarL|Candidatus Nitrospira defluvii
LTHERGSGSALITIAIVSRNQLLRLGLQAVIAPHEHLRLIGEAANSLQAVSLVSQEQPHL
LIIELEPGMDILGLVRKVKASLSTIRIIALHGIEDCRGGLEALSSGIDGLVLTTQPGAVL
LAIIEYLCRRPANVARCLPCDTSALERTRSTGGFEDRIPVPPDWSEDLTKRERDIITLIG
EGLSNKDIACRLSICSTTVRHHLTSIFGKLDVHSRQQLLIRAHKYGLVKLQANGTAARVH
LVAGSEQSA
>NIDE1487_RR_unclassified|Candidatus Nitrospira defluvii
MSLTMSSTKQTGRSRVMIVDPELQFGLKLADCLATNGYHAVLVRDLQSMLTELREIQPEA
ILLSSDSCEEKRGTAELDTLRALNVLCPQAPILTVVEPMPDASGTLSPPVDPRPSHQAPL
LHNRVEELLRANLGIPCVRASLT
>NIDE1489_RR_NarL|Candidatus Nitrospira defluvii
VTRILVVDDHAVVRQGVKQILSEQFHGAVLGDAQNAEEMILQVGKHSWDIVILDVGMPGK
SGLDALKELKQARPKLPVLVLSGYPEDQLALRMLKAGAAGYLSKDSAPNELVQALRKILG
GGKFVSAAVAELLALNLESDGEKPLHEQLSDREYQVMCLIAVGKSLKDIADDLCVGVSTI
NTYRARILEKMQLKNNTELTHYAIENRLVNRLIR
>NIDE1491_HK_Hybrid|Candidatus Nitrospira defluvii
VSTGPAHILLVEDNPGDARLLRELLTESGTGRLTLTHVDRLDAAIRCLTQAAFDIILLDL
SLPDSQGAETLVRMHEAAQGIPIVLVTGREDEELGLQLIQAGAQDYLVKGQTTAPLLARA
LKYAVERKRLEEELRKKTRFLQSVLDTMAEGVVMADERGRFQVWNQAAERIIGSGPADIG
IREWSKHYALFLPDRVTPFPTDDLPLARAIRGESVTDVLIFFHRPHWPGEAWLSVTARPL
LDDTGHLSGGVAVFRDITAAKRTDEALRDSQERYRLLVTKASDIIYRTDASGRFTFVNPV
AMRIMKYTEPELLGRRFIELIHPDHQPAAERFYGRQFIRKQPSTYYEFLALAKDGSEVWI
GQNVQVLLEEGTVVGFQAVARDITDCKRAEEARLESEERLRSIVQSTGDAIILMDTRGQV
AFWNSGAEKIFGYTAEQMLGQPVTRIIPQRFREAHQRGVERVAAAGRLTLQADMFELIGL
RKDGTEFPLEFSLAAWTAKSTLFITGIIRDISDRRQAESALRDSEERFRAIMDNSPALIF
IKDLAGRYLQANRQFEIISHLSHEDLVGKTDEEVFPPEQAAVFRGNDRKVLEAGAPMRFE
ESALHDDGLHTSIVVKFPLRNAQNRCYALCGIATDITDRKRAEEARQQLAKDRLLLLEST
GEGIYGIDRQGRCTFINSAAARMLGSLPEAFLGQDMHERIHHSFPDSTTYPRATCRIQKT
LEGGKGCKVDDEVYWRKDGTAFPVEYSSFPIIEDNQIIGAVVVFLDITERKRAEQQLTLS
HDQLRKLTARLESVREEERILIAREIHDELGQALTGVKLELCLLHDQIAEVSPMMRKKLE
SISTLVDGTIQSVQRIATELRPVVLDQLGLIPAIEWQAHEFQARTGIQCTLDVYLRAVTL
SHAGSTAMFRIFQEILTNVARHAQASVVHITLQEQAGSLVLDVRDNGRGVTDAELADPHS
LGLVGMRERALLLGGETIFTGSPGTGTAVRVRIPLDQP
>NIDE1492_RR_CheY|Candidatus Nitrospira defluvii
MVPELVKPIEILLIEDNPGDVRLTMEALKEAKVVNHLTVLKDGEEALTYLRRQGPYAHAT
RPHLILLDLNLPRKDGREVLAQIKAEEPLKRIPVVVLTTSEDEQDVLKSYNLHANCYITK
PVDLDQFIRVVRSIEDFWLGIVVLPVPPQNGAR
>NIDE1493_HK_Classic|Candidatus Nitrospira defluvii
MKTGLNNAPTKAGVVSDRSRSIHGRLPLVLLLCFVIATALGLYALSFLRTVLVEERGREL
AMNAAAVADTLDRVMFERFGDIQLFANDGILRDGTRPEKTARLLSYKQLYQYYSWLGVAD
ERGQLIAATDALPAQGTQGLSPESFELVRRTGTVYFEDMRPSPTSQRKMAIGFTAPIYGS
KGEFRGVVATRVPFEYLQPIFEQEGRLRYGEIAYDWLLLDREGTVLSEKNRPSLLNGGPV
KVDVPSHALAAAERDHPGFVQETHRRRGTPVVTGYARTRGYHNFHGFDWLVLFRLDRDQI
YAPVDRLIWMVGGIGLLVILPLTGYGIWASLELGRERNDLIKARQDLEQSVAELGRSNAD
LQQFAYVASHDLQEPLRMVSSYTQLIARRYKGRLDADADEFIAFAVDGANRMQRLIQDLL
AYSRVKTGGRQFEPTAMETVLKAALDNLTNAVKESHAIITHDPLPAVMGDEKQLAQLFQN
LLSNALKFGGAQPPQIHISAKQADGDWVFSVRDHGIGIDPQYAERIFVIFQRLHTREEYP
GTGIGLAICKKIVERHGGRIWVESERGNGATFYFTMRDEEPASSTQTLNR
>NIDE1562_RR_OmpR|Candidatus Nitrospira defluvii
MRILLVEDDADLAQFIRKGLKEERYAVDVASNGEQGFELGIANPYDLIILDIMLPVLDGL
SLCRRLRSTGVTAPVLLLTARDTVQDKVSGLDLGADDYLTKPFAFAELLARARALLRRGG
PQLQARLTAADLELDPATHRVCRGGNEIALTNKEYALLEFLLRNKNRVLTRTAIIEHVWD
ISYDPMTNIVDAHIRSLRAKMDRDFSPALITTVRGAGYMLEDEEAGR
>NIDE1563_HK_Classic|Candidatus Nitrospira defluvii
MNSLGRLIRRTALILMGGLLLGFSALIYVGGDTLLSRYVDGRLLELAETLGRIIEQRPDV
IRGAADELVVLGEKGRSQEEQHELREAAHSVRILSIDGQLLWKGSDVVPRPPVSASLLEQ
VKQGQTVFDMVQLREGSPVRRVSIPVPRRGQVRYMLQAEESLHFSKETLKGLAILLALGS
GLVILVAWAGSAWIARTVLTPIGLLSRRAETMSEADLGERLSLDSPFQEFHRLTHTFNAM
MDRFQKSCESQRRFVDYAAHEMQTPLTVLQGNLEVTLQKARSTEEYREALIGNLEQVEKL
IALARSLLTLTKVTGDRPPLHLAPVELEPLLQELIIELKLLADDRRISLALEVVPVPTIS
ADAQWLKQALINLLDNSLKYTPPGGSVTVRLRRSDGSLEIAVRDTGPGIEAEHVPFLFDR
FYRADKARARESGGTGLGLAIVKGIVEAHGGTVAVDTQPGKGSEFTIRLPLGRAPEGHPS
N
>NIDE1584_RR_RpfG|Candidatus Nitrospira defluvii
MGTHTSPEYVGTKPSVLVVDDETGPRDALKVILRPFFTIHSADNAKSALRVLKDQHIDLI
TLDQKLPDRQGIDLLQDIKQDYADIEVIIITGYGSLKSAMEGIRHGAAGYLLKPFNVTEL
ITLINQTLEKKQRLDYLRSFLKTSTALWGTEQEAGQAWRDLQANYFAIGKSAPELSANPG
DVTALIPLLSDLLEAKDRQLLNHCSRVSFYASLLANQLNLSLPDQKALALGAFLHDIGKI
SIPNYKYAADDDDGIKNGALAKAYSEAGARMLLPLEFQAEVGQIVAYHHERFDGLGNPHG
LEGEGIPLLARIVAIAQAFDNLTVDMPGHLPMSIDDAIRKIVLQADTHFDPKLTKLFAQV
VQECKSSLPALAIAKTSPTT
>NIDE1585_RR_NtrC|Candidatus Nitrospira defluvii
MKKRVLLVDDEPRVRASLRTVLEPTYEILEAADAAEGLKSFKHDTPDLVLLDVILPGTDG
LAALQTMRTENRAVPVIMLTGTKSVKTAVDAMKLGAADYLSKPFDVEELQIVIERTLGKQ
ELEQEVRQLRAQVVQRYAFHNLIGKSPAMQEIYAKIEQVADSRTTVLVTGESGTGKELVA
KAIHYNSARRERPFVALNCAALPETLIESELFGHEKGSFTDATARRVGQFELAHTGTLFL
DEIGDLSPATQAKLLRVLQEREFTRVGGVQSIKVDVRIVAATNKNLDEMVRKNQFREDLY
YRINVIALYLPPLRERGEDIALLAKHFLAKRIEEEKRPPQEFTKDSLELISHYPWPGNVR
EMENIIEQAFIWSKGSGTITPEHLPNILRTDTRSTSLRDDTLAGRLSLEKAVMEFEREII
LDALKRTTYVQTHAAAMLGISRRMLKYRMDSLGIGRPDNGVNPEPPLTQE
>NIDE1586_HK_Classic|Candidatus Nitrospira defluvii
MALHEHIRHTPILSTSEAPIRMIGAFAESVGQATGLPQVGECILRVLSEQLRLPEAAIWI
RDADGQYHLLASLGHSTRAALPASLPDKHALVTSLSDRLRLLRYDQTSSSPAGSAMMSIQ
AAVCLPLRNKTQLLGLCTLGPIGTNCHLDEETVIIAETVARIACTTLEHHLAQDDLRRSS
TLMRRTDRLRSLEIMAGGFAHEIRNPLTSIKTFIQLAPQRQQDPVFIREFSQVAIEDVHR
IERLLHEILDYASYMTPQPSDVDLNELVTSCLGFVSSTASHRGIRLRTTLAPQLPTLSLD
RQQIKQVLLNLLLNALDAMPNGNGVIQIRTRMLPLTGRTPWVQLEVEDEGCGIAPDHLEH
IFDPFFTTKHTNSASDGSGLGLTTAHQIVREHGGTLLVESRVGAGSTFSVNLPAPDARTT
VSAARE
>NIDE1587_RR_unclassified|Candidatus Nitrospira defluvii
MSPVEPSLNILLINEQPDEIKLVTSSLRGFFPGCRIEAGYSSEEALTFSHQGEWHIILID
HDLRPERGLDILSRLRRNAPYAAILLQTNESDSQTAVQALQNGADFLLFKRSPAFITELL
FSVQEAVEKRDLQMKLDHTFQRHQRFIETLSDLVYELDRDGRFVYVGTAVTAMLGYTPEE
LAGQHYSLLLPPLQEAAGRFRLNERRAGSRSVRRLELTLHRKALPDAPPASIAVDVTAKG
LFDSANRYLGTIGVLRDLSQQKAQQDRLTELESRLQETTRQLTLSREAARVSRQLQQPLT
TLLQDSQRLLSSIQHSKIEQHVETMVEQASQASQLGHQLAQAIHAPPLEFAPVDLHHLLE
TVVQSIRHETEGSGLLVTMHLAQHLPLILGSPGALEDLVRILLNYAHQYTSRPDAPSHLL
LQTAPPSGDAPSLVSRTLPLHSSTSREYVSVTIKESAGRTATPVGEQPDFHISPEQFFRA
HQIVRAHGGAIEIEHAPDSGLTITVRIPVPAHLFSDEGTESSTALPATPDLARRQSQPIA
GQRPDRRRSERKLFALPVQLSIGGTTLRGVLRNMSTGGALLTIHDLSASIHLQPAYVVIK
TPVSFLELQGVVHERPAALTDLPLTAIKNFVISFSSSGERDRNVLRSLLDGLQDGSTIVT
FEGLILPFFTTAEHNPDASRPSIATPTERREAARLHVPCPIRLLGSPVTPTRPLGVTVNL
SLEGACIEVPGGHDFPVGRQILHLAPVEPNTSSIGAALPEGSENPWPARIVWTSQPRTRP
TLNLPQTEGLRRFGVRFEGLSPAQEQKLRALISSRIATSQDLAEPLSDSPVLTVSHNLRN
REGLTIALCHDVPTRTDSTQYPLVLLCPGYGTTQQAYVALAYTLAACGLQILRYDHSRHI
GLSDGDPTQTTLTSLEDDLDTVLSFAQKEFPGIPLTVLAPDLLGRIVLRRQDWHRRVNRL
LLLNPALDIRNCLTSLHQRDLVGEHLAGTRLGLGNLMGIPLDIDHFVADAVTGRYTENTA
LQEDLSHCGTDVVFLTTGPGTAEYPTPSPAPALVEDALHRLGSRGSRVMLQAPLLPADAV
APTALIASWQRIAQLCLASDRFPHPTVPALLDLSRITSTRARFERDRLRIKYAAGTAGRE
RLWAAQTDLTRSLDELPAHWQYIDQLYQLLQPLDGGLALLDVGCGIHSFARLLLLNLSYR
LRAQTWNQNQPLRYIGVDFSVAALHAAQDATNDALKHVDRLFSGRISGPTPVSQQWVLGR
SVETLPFADHSFDRVLANLSLSFSRSPLHALRELFRVLRPGGKLIVSAVTPLADMAIPYR
PSLQELGVDAFSGDARLALNRMAQCCVALRVGQLHAFHEEGLSTALAQVTSAPVRLVRMF
SGQILVALAEKPDSAG
>NIDE1688_RR_CheY|Candidatus Nitrospira defluvii
MPSSILLIDDSPGECELLRQALTQSGYKGRLEITDGSRAAMTYLNDHVLSDEPGLILLDL
KLQGERGVDVLKRLKQDARLAPIPVVILTSSDDAVDVRACYQAGANGYVVKPGQFDDLVS
LSLHLWKFWLEHNCTRRIATPC
>NIDE1735_RR_unclassified|Candidatus Nitrospira defluvii
MGSTIFVIDSSPAVHRMVEQISAPEGHKVMGFSDGPSALDAARTLSPALVIADYHLENIT
FSGFCKEIGRQDSLAETLIVSMVDGSDRLDESKLRSLGVRALLKKPLQREQLLDTIKGIL
NGAAGNPRGGKPAKTRTWPPVSTGTDDEDDDSPNNASLDDAPHHEMEKEHSPMSPSLSPT
TAPASSAPVSNGPSGDALMKGLFDHLLQSVAAQADRKIRELLPAAMAKEVTGQVSLAVGK
VVQTEVAKQLADALAPERLQTAMRELIQEELKRQAQTQLAGVETTVRQAVAELAPALLEQ
STEKRLGDLMDTGVKKHLPEALKSHLEMIDQLVKKEVEQVAANRARQAADEIVHEMAKDP
IRQAVQRIVPDVAETQIRAEIKRLSSPD
>NIDE1763_RR_CheY|Candidatus Nitrospira defluvii
MATIMVIDDEPSIRGLLREVLERSGHKVVEAKDGREALDLYQKHKADLLIMDLLMPEVDG
LEATLQLTREYMDTKIIAMTGAQGDRNFLDIAKLFGAHRTFEKPFDLKEMLNAVEAELAQ
K
>NIDE1772_HK_Classic|Candidatus Nitrospira defluvii
MASTHRRRSKASMPVRSEIAAAEVLAWLSDCIHGGLCFVCQGLLIFENSQFAELVEGVSP
RVGEGEHALRRRLLDDAIDWNARALGSRKTVEYTVADRDGRPLYYACRLNVVPYRGERGV
LMVLEDVTERVVLAQDASHVARFQSALARIGTLAVSGLSAQALMNEAVQETAAALEVELC
KILVPREQDGHLYIMAGIGLRSDLIGKLTIEGGTHSQAGYAIRERVPVVVDDFRRETRFS
ASKLLTEHGAVAGMCVPMLVEDRVYGVMTAHSKRVRKFNQKEQEFLCTMANTIGTVLERR
RHEETQMDFYHRLFLSAQDGVMMTDTTGRIMEWNPALERMTGWPREEALGRRPAILKSGK
HPPEFYERLWASIRAGHPFVERFVNRRKDGSEFLVWESVSPVKASDGTTQYFMAILTDLS
EREQMLEALRHTEQVKLVGQLAGGILHEVRNPLIGLGSLATHLADQASLPQEARDRCRLI
AREAARIDELLESHLGQLRPRPFDIAVCELPAVLDDTLTLLRPNLIKNHIRVKSSMAPDL
PAVDASRAHILQVCLNIAMNAIDAMPAGGSLNVTLSPDVRRVPGVLMRFADSGKGIAGED
LTHIYEPFFTNGKAKGVGLGLTITRDIVERHHGQLVIQSPPGSGAVVDVWLPLKHEA
>NIDE1773_RR_NtrC|Candidatus Nitrospira defluvii
MAWHLLLLEDEASVREAFALRLRDQGYVVQTAESGEEALGLLRSFEPDVLVADLVMPNLS
GLEVLARVKQLSPALPVIVLTARGTVKDAVEAMRLGAFDFVAKSIDMDDLLHTLRRATEF
LTLQRQVQLHSGQDVARYALDRVIAKSPVTRSFLAQVQELIKNDRVTVLLQGETGTGKQY
MGRVIHYNSPRAGRPCVEVDCPSIPRDLFESELFGHEKGSFTGATGRKCGLIEMAEGGTV
FFDEIADLPLPLQAKLLRVLEERTIRRVGSAATIPIDVRVMAATNRNLKEAVAKGEFRED
LYFRLNVVTLTVPPLRERREDIIPLAEQFLNRSALALKKPVRTLGESAQVLLQGYHLPGN
VRELSNLIERAVLFCAGTTLEAANFPIDVQAAGSMPVAASLDASSAEADGSDSGDVHISF
RVGAQSLADLEDRIIEAVLAQSGGNKTLAAKQLGVTRWMLDRRRKPRV
>NIDE1858_RR_unclassified|Candidatus Nitrospira defluvii
MSILIIDDFQEERDLLFTILHSAGFGPLLPVGTAREGLQLLGVGKRGKQASGIDLVLMDI
EMPEIDGLEACQRIRMEEQLQGLPIIVITAHTEAKDIQAAYTCGATDYIRKPVIPAELIA
RAANALSLKQEIDARKLREQELLERTKELDHAFEQITTLHGTVHICAKCKRVKSDGPHWQ
RVEDYLRREARAKVAETVCETCLHQAYPHLK
>NIDE1859_RR_unclassified|Candidatus Nitrospira defluvii
MTRHSPRFTTTGLLVLLTGLIFLAELTSEFRLATWLPYFFLTIPAARLYPRHVVLSAVGG
WSLLIAAGFLAPFPADEATNALVSRAIGLLGIWIIAYQLDRQPAACDLREISQPTVPGSE
ERQVQGPASQAPEPVLPRVPAEPAEQKTRVLLVDDSIESHTLMRFYFRNTPYDLEIASDG
EQAVATFKTGRFDFVLIDLHLPGMDGFSATRAMRAWETSRKRPSAIIVALTASSLADTQA
QSLAAGCTELLTKPITKAQLFNTLRTYHPPSPACDTTAAQALESSNVTERIDEELRRRRP
AFLANRRMDLTMMQDALVQEDYDAIRTTGHRMKGLAGSFGFPDIGAVGQQLEQAARSRDR
AAIRRELDGLATILAGVDQAA
>NIDE1870_RR_RpfG|Candidatus Nitrospira defluvii
MSIPSVTEVTTQQAILENRNILIVDDEEPIRRLLGYLLEPHGYKVALAGEAREARQRMES
GSYALVLCDVNMPGESGMDLIRHILTQYPSTAVIMITGLDSPVLANAALDMGAFGYVIKP
FEANEVLINVANALRRRKLEIENAMHRENLEEVVRTRTIALQQALEWLERSEKELRLSRE
ETIQRLAIAAEYRDSSTAQHIQRMSHYCELLARRYGLSPERCDLIRTASPMHDIGKIGTP
DHVLLKPGKFTPEEFKVITQHTEIGYRILAGSDSELLKVAALIAWTHHERFDGTGYPRGL
KGETIPLEGRITAIADNFDALTTQRVYKPAYDFDHAKELMLKERGKHFDPELLDIFFDSM
EEITRIYDQFADPTWLSSSRHRTITQDQGEVA
>NIDE1908_HK_Hybrid|Candidatus Nitrospira defluvii
MASLLAWFAHGRLWHFVWGSVVLSCLLSLLFSRIIHGHIAWDYPFTAGLISLLVSSVVVL
LISRMRALEQTLADTRRDRALDLAARTQAEESLRESEERFRSFMDHSPAIAWMKDDQGRH
VYVNRVFEHRFQMVSGQWLGRTNFELFPEEVARRFQTHDQMILADGLPKEFVEVAPDPDG
TQRDWWTFKFPFRGPAGRRYVGGVAIDITDRKRMEAALLVSEERLRLALGAAQAGIWDWD
IRTNAVQWSDNVSTIFGLSRETFVGTYEAYLALVDPQDLDRLLQAIRQSIQANVEYQIEH
RILWPDGTVHWLACRGDVLRDADGTPVRMVGTVLDVTARKEMDLKLANSEAQLRAILDHS
PALIFLKDREGRYLDVNRQFERAFNLSREAILGKTDTELFSPKQAAVFQTNDRLVLEAKR
PLRFEETADYHDGPRTSIVFKFPLLDRDRMLYAVGGVATDITDRKRAEEALALARDQAME
AARLKSEFLATMSHEIRTPMNGVIGMTNLLLESALTPEQRECAEVVRNSGDHLLMIINDI
LDFSKIEAGRLTLETIDFDFRGMIDDTLDLIAEQARQKGLDLVGLIDASVPSAVRGDPGR
LRQVLINLLGNAIKFTDRGEVVLRMTVAQDAQSHVVLRGDVTDTGIGISPEGRNKLFQTF
SQVDASTTRRYGGTGLGLAICKRLTELMQGEIGMESAPGKGSRFWFTVRLEKGAAARATE
PESLPTLDGQRVCLAGKPGSSHTFLEQAVASRGMQGVAANDGTEAAILMRKAAADGHPFD
LVIFEEQLSGGEGAAFAQTMKADPALRMIPVIVVTSFGQRGDAGAARDAGVAAYLTRPIH
QAALWRCLATVLAPVSDPSGQTAAEEGPMRPLITRHSMQEQTDRGRPHVLVVDDQKLNQV
VAVSLLERLGCLVDVAESGQAAAEAVAATSYDLLFMDCQMFGMDGYQAAALIRKREGGGP
RVPIIALTGHMQQSDRAQCLAAGMDDCLTKPLQFTLLEAMLRRWLKKDVDPGR
>NIDE2020_RR_NtrC|Candidatus Nitrospira defluvii
MKPIVLVADDDPSILEILKLGFRTKGYEVITASDGKSAIQAIEQNRPDLLVLDIEMPHLT
GIEVLRHLRKDWPTLPVVIMTAHGTISLAVEAMKEGATEFITKPFEMEQLLLVIQKALER
EGLRREVEVLRNEVDSRYETISSVNAEMLRILTTAQKAAQSDATILLLGESGVGKDLLAR
CIHAWSPRRNKIFTPVNCVALTEELLESELFGHEKGAFTGAHTQKLGKLEVAAGGTVFLD
EIGDMKPALQAKLLRFLQNREFDRVGGTRSIKVDVRIVAATNRNLQQAVKDGAFRADLFF
RLNVVSLTIPPLRNRQEDIPQLIERSLARLCRDMKRPMSHMSPSAIKKLASYAWPGNVRE
LENAIERAVVLKTGNLLEPEDFALHSLELQQQESPVNYLPFHDSVEHHKVFIIRDALAKT
GGSRAQAAELLGLQPTYLSRLIKQMNIS
>NIDE2021_HK_Classic|Candidatus Nitrospira defluvii
VLPEPQQAETLTQHFTPRGTVRREADLRLLRRDRELDAARRVSEALFQHLTPDDMAIRAL
EIALETVDAESGSILLADSATEQLVFRHSIGDSRVKAGTAIPWDRGIAGEVFRTGIPIVI
RDAHADPRHNASIDQMLGHVTRDMIALPLKRWEGDSIGVFEVLNKRGGRLDDDDLAILTI
VSAITAASIEQARLFQDAKLAEVARIVGDIGHDIKNLLMPLVCGAGLLEGEMKDLVARSA
DLSGATAKDTFQLCAEVIHMVRGSSRRIQDHVAEIADCVKGLSSPAKFAPCRIADIVGSV
YDTLRWQAQEQGVMLCRAGLEGLPTIIADERRLFSAFYNLVNNAIPEMSAGGTVTVYGEA
DSPAARILLHVADTGRGMPDEVKDSLFSIRVVSRKVGGTGLGTKIVKDMIDVHQGRISVE
SVLGKGTTFHIQLPIVQP
>NIDE2070_RR_unclassified|Candidatus Nitrospira defluvii
VTELPPPQILIVDDDPDIALVLHDLLEHVGYRVSVAGTGGEALAKAKAESLSAVVLDLML
PDMDGLSVLTLLKQIDPVLPVIMLTAFVEVAKKHSSLTEGAFGYLTKPYDAEELKALIRR
AVGVKHLSIEAAATKQALTASEDRFREVVQTAPDAIVLADGEGKILSWNSAAERLFGYLA
GEVLGESLTMIMPERYRARHDQALARVRTTGDLRLKGTIVTMHGLHKGGREFPIEMSLSS
WISDGQRVHCGIVRDITVRKEAETRLLQQQIEQQVLLDLIPAMVWYKDSHNRILRANRRA
ADSIKKTVTEIEGRSTDEFYPEEAERYHQDDLEVIVSGRPKLGIIEPYHTGSGEKRWVQT
DKVPYLDPQGKVLGVLVFAQDITDRKQTEEALRESVDCLRVVMESASNGIIIADAGGKIL
SANTQVEAQFGYERGELLGHAVERLMPARLRPPGSDRAGVFLIGPDDRSVSPVCECVGLR
KDGTEFPFTMTLTPLMTTNGIHTVVAIHQAQGIA
>NIDE2119_RR_unclassified|Candidatus Nitrospira defluvii
MKILVADDTIVNRRILEALLGKDGHTVVLAEDGKQAVALFEQEQPDLVIMDLMMPEMDGY
QATKLIKQQTGSRFVPVIFLTAVTNEDVLAKCIAHGGDDFLTKPYNHTILRAKIAAWERI
QNLHATVTAQKDELEGHHARFLHEQDVASTIRNNVLGGGCLDQIGINYHLAPAATLSGDL
ILAATHPTGVLHLMIGDFTGHGLSAAIGALPVADIFYRMTERGFTLRDILIELNRKLKRT
LPTGLFCAASLVELDARRGSAAIWNGGLPDVLVFNSGAGCRLQVPSQHPPLGVLDEADLH
TGMQEVSLEPGDRLYLYSDGVIEACNPTGNQFGESRLIEGLTNNREPDRLFDEILASLTS
FTAGTVQQDDVTLVELPCDLITARLLAPETTAPPQPPWPLEWRMELSLSPDAVRAVDPVP
ELLQILNQVPGLPQHKERLFTILAELMTNAIDHGLLGLDSSLKHSPEGFDAYYRERDARL
AELRDGQVRIALTHVPLHRGSQLTIRIEDSGPGFDFTRPNTDLAMNDTGAGRGIALISSL
CQKINFHGKGNCVEVVYALEPAA
>NIDE2265_HK_Classic|Candidatus Nitrospira defluvii
VRLSIFWRLILTYVVIIAVMTAVNIYALLQIRTLAGLNTEVGSHHHPEIESAKRLLSSFY
QQIQSEKKYVAVPAATFLEHFDAESKDFQLVLHGLLTRDTSEPEIQLVREVERIQQAHLA
LFHAQLAEGVGQLPESSAAYDERRDALAGKMASTLQQYIGLHEARIAVGVNESHASSVHA
EAVTRQLVLVALMFGLGMAAVASYNILRPLRRLQSTIQEMGQGNFRATMDGQAPRELREL
GDTVKWMGTRLQQLDDIKSEFLAHVSHELRTPMASIQEGTHLLLDEIPGPLTQDQRTTLR
IMSDSSRRLMYLISTILDLSKMESGMMEYRFAPTDLRRVADISVNKIRLLADAKQVRLLV
EAPVERHWVRADSARIEQVLDNLLSNALKYSPEGAAVTLHMEPRRDEGLMFVDVTDCGPG
IPTEEVPHIFERFYQGRTKTRHVSVGSGLGLALAKKVVEAHGGRIWVDSEVGKGTTVRFM
LCLTKPGILA
>NIDE2267_RR_NtrC|Candidatus Nitrospira defluvii
MEQERILVVDDDEGLLHLLRMRLSALGFSVTPCTGGRDALTAARQETFDIAITDLRLRAE
DGLALAEELMQIQPGLPVIILTAHGSIPNAVEAMQRGAFGYLTKPFDDKELKATLDKALI
QLRMTREIQRLKSLVKELYGLENVIARSPAMQRLFQQVAQIADSDATILLTGETGTGKEV
LARVLHANSRRSKGPFVALNCAAISETLFESELFGHIRGAFTNAVAAKRGLFQSAHGGTL
FLDEIAEMSLPMQVKLLRAVQEREVREVGAEYATKVDVRIITATNKDLAESVKAGTFRHD
LYYRVSVVPLALPPLRERKDDIPLLAQHFLKQSAKRSNKDVRGFTPAAMHRLMVYPWPGN
VRELENAVEKAVVMSRQDMVLPELLPTAGATSDIGLKPLTEAKEDFERTYLRNVLQMTGG
NISRAAQFAGRYRADFYKMLKKYGLHPSMLKERSDFELSDLEEVTEEVKDA
>NIDE2280_RR_NtrC|Candidatus Nitrospira defluvii
MSQSHILVIDDDPAVRQILAETLTGEGHQVTVMSSGLEGVEAVKDQPVHVVLTDLQMPGI
DGLETIDRISKIDSKIIAIVMTGYGTVDYAVRAMKAGAFDFITKPFEPDTVAVVVRKALD
VYKLKQENHLLRKAVRDQYRLEHLVGTSAPMRMVLDFVEKVADSDSTVLIEGESGTGKEL
IARMLHFNSMRRERPLVPVNCGAIPETLLESELFGHEKGAFTGAAHTRLGRFELAHGGTI
FLDEVGEMSLPLQVKLLRVLQERCFERVGGTRTINVDVRIIAATNQDLAQAVQERRFRQD
LYYRLHVIPIHIPPLRERRSDIPLLVNHFIAQFNQLRRTEILGMEPDALARMMEEEWPGN
IRELENMIERLCVLKKRGMITMGDLPERPVKMNAGKGVESPEQFIRFSEDGINLTKELEH
YENRLIGEALRKANGITSRAAQLLQVNRTTLVEKLKRKGFDPKTHGYSIQN
>NIDE2283_HK_Classic|Candidatus Nitrospira defluvii
MTTREVDTSNNDLLTRAFHDFDQAATVLQQSYDALTTRLQQMDLELAQTNASLREHLRET
EEMRAHVTAVLESLDTGVIVTDSQDSVVRCNHATERLLGVSQASLKGRRATEVLEEIRKD
HGEYPLVLPTGVTIALSQSALTDETGTLIGKLVLIHDVTHIRQLEDRLQRRNRLEAMGQM
VGNIAHEIRNPLGSVELFASMLRKDLRDQPHLRTYAEHISMAVQAMDRLLSNLLVYTRPD
CSRLAWLDTESLIREVLTLASHAMSPASIVVRCEVDPRVPKIWCDGGKMKQVLLNLVLNA
VQAMPEGGSLTLSARMAPAGISEAPAIQLTVSDTGTGIPLALQSRVFDPFFTTKDQGTGL
GLAIVHALVEAHHGRIDVESRPGHGTSFVMTFPQGSMQQATMPARNAALVGRSVQISPIA
NVTEEETYE
>NIDE2284_RR_NtrC|Candidatus Nitrospira defluvii
MSVQQDLQGPSATSEDTRMVLIVDDEPSMRTALSETVRRLGYQVRGAIDGVDAIEQIERI
KPWLVVTDLKMPRLTGLELVKAIKQKSPQTFIVLMTAYGTVETAVEAMKYGANDYLLKPF
STDLLERVILNLQATTATDEQEGPATLEARAILTQDPGMIRLLTTLEGVAASQATVLISG
ESGTGKELMARYIHARSPRAHRPFVALNCAALPDSLLESELFGHERGAFTGAIQKKLGKF
EMAHTGTLFLDEISEMNLGLQSKLLRVLQEREVDRIGGREPVPVNIRVIATTNRSLYHEV
TQGRFREDLFYRLNVFPVTVPPLRDRSGDIPLLARHFLRSSAQRNGLTMPTLSERAIADL
QQRPWKGNVRELENVMERAILVATGGAVDVDHLMPGDGTVPVREVGAVDTLVTASAHGSL
WEMERDLIFKTLARVKENRTHAAKELGISIRTLRNKLREYRDMGYQVEAEKS
>NIDE2290_RR_unclassified|Candidatus Nitrospira defluvii
MGTVDLGSRLPQTSPADNEKELAPRAILIVDDEPSIGFLLTEMLQSTGHPILTAGSVSEA
LAHLKSRPIAVLIVDVQLAGTDGIAFLQQALEVDSRLLSIVMTGHGNIELAVRAMKSGAA
DFLTKPFEVELVRQSVSRLLELYRLRQENTVLTRTLIRSGNIQLRTVPLADFSRGNRPFG
TDDVTEFERGVAEGEKRVTERVAALRQREQALVASLMAQLEGSWRNLHDTVEEEVASLSF
MIAQKVLRELVTEKREVIVTQVRTALAHLHESGLVRIRVHPSDLPLLEASRAALSQTPHG
LLTLKFETDPGISPGGCLVQAQSLLIDATLDTQLLRLGEALRKRDAGEA
>NIDE2323_HK_Unorthodox|Candidatus Nitrospira defluvii
VTNHPQHPRTPHPQHAAGLSVPPEVLTLLWDAVPLGIFLLGAEQTVIFANRTAARLFARS
PAACAGHALSDLLGQRLDLSDSLRATGIVKLPDGRFSPAGQTASDDESDTGHSTVIEWQH
LRISGIPSVATLMTLRDVSREVELEKDRDRLAEVAEESPYPIVEIDRHGNLVYANPAMAD
VLGRFGYDLAGKPEILPDNLPALVATCLLEGRTLTSQDVVRGEACYSWTLCPVPGHGLVR
AFAIDLSEVHATHRALNETADRLRESNRQLDQALQQAQTAARAKSSFLAMITHELRTPMN
GVIGMASLLLETPLTEEQRSFTNTIQQCGEAQLSLINDVLECSKIEAGKLELEHLDFYLR
TTVEDVLSQFAERAQRKGLEITGLVHAAVPNALRGDPGRLRQVLTNFVGNAIKFTERGEV
TLQAFLERDSPSEVIIKFEVTDSGIGISEDVQSRLFQAFTQADSSTTRKYGGTGLGLAIS
KQLVELMGGQVGLRSQPGQGTTFWCTARFQKQAVCAPAIVPSVELSGRRILIVDDNESNR
TILHHLVSGWGMQDGQARHADEAILMLEQAAAQGRPYDAAVLDMLMPGKDGLQLAQEIRA
HPQGAGVRLIVLTSLIQPGHAERARRAGFTAYLTKPVRHDQLQGCLRVVFGLQGPATTNA
PGVATGPTIVPTLITRHTLAEQRARPRILVAEDNVVNQKLAVRMLDRLGYQPDIVSNGQE
AVAAFERGLYAAIVMDCQMPTMDGYEATRRIREQEQKPAASGTRAHIPIIALTANAMPGD
RERCKAAGMDDYLSKPVKTDDLGRLLQRWAPLATPDHAPAPTPPREMSKTDARVFDASTM
LVNIGGDVDLFDQLIRLFLERHRIMVQEIEAAVKQADGVALERAAHSLKGTAANLCAPEV
VLLASQLEANGRLGTLAEAPALFSQLERTVQQLVAVLERQIAPTDPAQSR
>NIDE2348_RR_CheY|Candidatus Nitrospira defluvii
MKILVVDDMSTMRRIVKNILKQLGFNNLEEAENGQDALTKLKADTYGFVVSDWNMPVMMG
IDMLRAIRADEKLKKIPVLMVTAEAQKENLMEAVQAGVSNYVVKPFTAETMQEKINKIFK
>NIDE2350_HK_CheA|Candidatus Nitrospira defluvii
MSDEMQEILNDFLTESNEMLEVLDQRFVTLESDPTNTDLLNEIFRAMHSMKGSAGFLGFN
HLVDVAHRGENILNKLRQAEMAVSPAIISVILETIDVIKAIMADIRESGTDNHVVTAAIA
SKLDDILNGTAQSAPPASAHVEPTPAATKVEASTPAQEAPAAAPPTLGEILVNDGLASKE
QVFDALTAQQHQPEPKTPLGEILLQAKAITERALDQALHKQEKTPKPAEEDATIRVETKR
LDSVMNLVGELVLGRNRLIKIGTQLEQHHESDPQVRVLSETLAQLNLVTTDLQLAVMKTR
MLPIKKVFAKLPRMVRDLSQKLNKQVHLEMRGEETELDKSVADEIGDPLVHLVRNAIDHG
IETPAERQAKGKAGEGHLTIAASQEGNSIVIRINDDGRGIQVEKVKEKALAKGLISEAEL
ATMEHREILNLIFLPGFSTAEKVTDVSGRGVGMDVVRTNIRKINGSVDLESEPGKGSQII
IKLPLTIAIIQALMVEVERSIFAIPLSTVIEAVRISRSEIKTINGREVLHLRDRVLPLIR
LAQEFDIPTDADRERFYVVVAALGDRRVGVVVDELRSQEEVVIKSIWDYLETVKGVSGAT
ITGEGKVVLILDTSELVQNAQAWHNPGIAA
>NIDE2351_RR_CheV|Candidatus Nitrospira defluvii
MSTLINEIDARTRLAGANQMELLLFKLGTNEIFGINVFKVREVMKLPELTQIPEADSRIV
GMANIRGIMVPVVGLKRSLGLGMETDGQGNGSPGGNPYLIVSEYNGSLQGFLVAGVDRII
RFSWSAIKTPPAIVRENNKGAVTAVTMLEDGRMVLILDVEKVLNDICPRTDDDVFASMTI
APELRSKCVLYADDSSVARMQIRKALDRLSMSYVIATTGGEAWHKLQALADQATAEGKER
VDQIQCILSDIEMPEMDGFTLTKHIRADPRLAHLPVMLHSSLTGACNMEKGRTVGATDYI
TKFDAKMLAEKLALYIQNPNANVKKTA
>NIDE2352_RR_CheB|Candidatus Nitrospira defluvii
MALPLTQPQSVANPVRVLVVDDSAFMRKSLTTMLEEGKQIQVVGVARNGEEAVQQVQQLK
PDVVTMDVEMPGMTGLQALQQIMTKNPVPVIMVSSVTVEGAQETLQALEWGAVDFIPKQL
DGVASKISEIQKILVPKVLAARYAGSKLKRLNVTGTPRAAVPVAKALSSRSVSVTRGTKL
IAIGCSTGGPQALFEIVPTLPADCPAGIVIVQHMPSSFTKPFAERLNNLCALEVREAVDG
DEVKPGRVLVAPGGMQFRIVKKTITTSVVKLSPNYEKHPHAPSVDIMLQSVAALFGERSI
GVILTGMGHDGLEGMKAIKAAGGRTVAQDEASSVVYGMPKAVVEAGCAEKVVALSKVIGE
IMNMV
>NIDE2360_RR_CheY|Candidatus Nitrospira defluvii
MAKTVLVVDDSPTMRQMVAFTLTSAGYQVVEAGNGKEAVGKVNGGAKPDLVVTDLNMPEM
DGITLIKEIRKMPALKFTPILMLTTEASDDKKKAGQAAGATGWIVKPFNPEQMMAVIKKV
LPG
>NIDE2361_HK_CheA|Candidatus Nitrospira defluvii
LTDDEAHHMSTDLSHFKDAFFEESQEHLTTIEEGLLQLEQRPGDIDLLNRIFRGAHSIKG
NSGMFGFTAVSQFTHKMESVLDQLRSSQMVVTVAITDLLLQSLDCLKTLIDCARTGAAPD
EAHVAALGGRLEACQGTPAPGQATAVPAADERSLPPGTHRFTITWAPPRYLFQRGLDPAQ
FLKELASLGTVTHLALDAGRLPVLMELDPEQCYLGWTLELETGKDLKVIDAVFDFVREDS
TLTIVDNPVETHPTAAVSDGAKPLGEILVETGVVSQTQLNQALSQQKKVGEILVEQKVAT
PEQISEALKKQSECTVPAKKAETPSIRVDTVKIDRLINLVGELVITQSMLSDLGSRFEMS
QLPVLLERVAQLERNTREIQERVMGIRMVPIGNAFSRFPRLVRDLSGKAGKKIQLILSGE
ETELDKTVIESIGDPLTHLVRNSADHGLEPPDERLAAGKPEQGIIRLNAFHEGGSICITV
EDDGRGLNRDKILAKGIKQGLIAESDKLSDEQIWMLIFKPGFSTAEKVTDVSGRGVGMDV
VKRNIEGLGGTVSIKTVTGKGTTFTLKLPLTLAIIEGMTVRVGQDTYIVPLLSILESIQP
KREMLKSIVGKGELVNVRGTYLPLMRLYDVFRLEPELSDPTKAILLILETEGERVAVMVD
EILGQQQVVIKSMEQNFRKIEGVAGATILGDGTVGFILDVRGLLNISRNGTAQAA
>NIDE2367_RR_CheB|Candidatus Nitrospira defluvii
MAKIRVLTIDDSALMRQVLAELLSKDPAIEVIGSAPDPYVAREKIKALNPDVLTLDVEMP
KMDGLTFLEKLMRGRPMPVIMVSSLTESGCQTTLRALELGAVDFITKPKIDLREGMDNLA
DDLIAKVKGAATACIRRGAPVSSPDGARPSVLSSAMIKTTDMIIAIGSSTGGTEAVKEVL
QVLPPNTPPVLITQHMPERFTKTWADRMNQLCRISVKEAEDGDSVLPGHALIAPGNYHMT
LVRSGARYSVRINQHEPVNRHRPSVDVMFDSVAQYAGGNAVGVILTGMGGDGAKGLLRMK
EAGAYTIAQDEASCVVFGMPKEAIKLGAAEIVRPLNDIATTILNHVTRA
>NIDE2370_RR_RsbU|Candidatus Nitrospira defluvii
VAEPAHRIVDDPLAGKAAKPMPVILLVDDDQITRISMAGRLKRLGYRVIEAGDGIAGLAA
IRAQRPDLVILDWMMPGLDGPSVCEAIRADGELRSSQVVLMTAHDQPEQIAEGLSRGADD
FLSKAASKQEVLARVQASLRSSALVREIERTRDDLDRSHRLLSAKQTELESELQSAADFV
RAQLPLPGMPAPGVSMQWAYQPSLALGGDLFQVSVWGSETLGLYILDASGHGVAAALRAV
ALMTFLREDNLAKVVGSFDPGAIITEANHRFPLTQDGEYFTLWVGRLHLPSRTLSYAAAG
HSGAFLHSLQGVSQWLSSASLPLGFDPTISFDSATAQLLPRDRLYLLSDGIYEAPSPTGE
LWGRDRLQATLESHRAHTLAHSIGDTMTTARQWLKGDIFPDDVALLGVEVLDGTAPAKEK
S
>NIDE2371_PP_HPt|Candidatus Nitrospira defluvii
MDAQPVMDLAAAMERFDGDQDLFLTLAEMFLERSPAALAAIQTALADQNLPMLAKEAHKL
KGSAMEFCARPTVAAAAQLEESARQSAVSDMAAIGERVQAEVQRLTAALQVIIEKGFPS
>NIDE2372_RR_unclassified|Candidatus Nitrospira defluvii
VTRPAASRTLLIVEPCAETLAMVMEQAKTRDLSIMTAPDPHVALAMMDMASPDVLMTDLF
LPEPNGLMLIREALKRNTRTAVIATTRAGNEQALLEAVRAGAGDCLYKPAQGEELGVALD
RALRRIPQTIDDIPGIEQLEYRLVIGTDPGDVESCVAWLIESTAMELPETQRLHLRTTLI
ELIVNAVEHGSLEIFYREKHEALSTDRFDALIDERRRNPRFAQRRVIVRALYDKFYRRMR
YAITDEGNGFTWNRFLTRSDQPCDSRDANGRGVFLAKAFFPDLTYNERGTEVTFSVPLP
>NIDE2412_RR_OmpR|Candidatus Nitrospira defluvii
MGLEIIQIVEDDHSQAKLLDQILRQASFRTNVAFDGPSAMQDVWRIKPSLIVADDNLPGL
NGREMCKRLRQDPSTKHIPFIVLSGYSSEERRVEALDSGADDFIVKPYGAAELVARVRAL
LRRTQQGQGQEEELGEDLALTENLYAVEYRGRKLILSTEEWKTLRRLVGSVGSVVPREEL
STLLWGNDALLHDGEMDRCMEQLNTKLTGEGPAVGSIKIVPGGFRLLLPSSEKSDVLPAR
>NIDE2426_RR_OmpR|Candidatus Nitrospira defluvii
MTASIVQIIEDEPLHADLLDRALRQAQFATTLAADGESGWRDAQRLLPSLILLDLMLPGL
SGHEVCRLVRRTPSTRHIPIIMLTAVGTEADRIAGLEMGADDYVVKPFSPREVVSRVQAV
LRRVHETRREDPVLFSDASITMEGPYFVLSLQERQITVSSTELKLLQYLLTRDGELVRGD
DLLKLPGEELGNASREELDHRVRFLRRKLENSGTGSIEILPGSRYRFLAHPRPT
>NIDE2437_RR_OmpR|Candidatus Nitrospira defluvii
MTDRTRSILLVAVASAAEHALAPVLKTNGYTLTVTSTLAQALAEIRRAPPALILLDRTWI
ATAALQRTELPVTIPIIVVQPFDQSCGPDECLTELDAGFDLMFCSPHYRELLAHIRAILR
RHNMTSAPPSILRVEGLVMDIARHEVTVGGALVELTPKEFRILHQFLLSPGVVLSRQDLL
NRVWGEDYALEEHALDVHIHSLRQKIEADSSKPSFIVTIRGIGYKLQNP
>NIDE2522_RR_PleD_VieA|Candidatus Nitrospira defluvii
MSQTHPTILVADDDPLSRLFVQNALEPAGMTVVEATGGRDALAKFETLMPDLVVMDIMMP
DLDGYLTCSRLRTLPRGKRVPILVLTGLDDANSIARAYQHGATDFITKPVNATILCHHVR
YMLRTNNVLHALIRSESRLELAQRIARIGNWDWNPKTNRLSMSNELCRLLGVRPQDFGGT
FEAFLNLIHPDDRPVVTGALERLVSQHTPCDIDHRVVLPNGTDFIIHLQAEGVREEETDE
LTVIGTAQDITERKQAERAIHQLAYYDSLTGLANRVLFKDRLSNALSYAERYHQHLATLF
IDLDRFKIINDTLGHTVGDRLLTHVAERLSESVRQSDSVGRHADHEPTHALARLGGDEFT
ILLTALPTPEDAGRVARRILEALAHPFSIDGHEIFISASIGISIFPSDGATVEALLKNAD
TAMYHAKEQGRNNCQFYSSGLNAAAAERLDLENELRRALEREEFVVFYQPKLNIHSRKIL
GAEALVRWKHPKRGLVPPGVFLNAAIDTGLIRPMDEWVLREACRQVKAWETAGLAPITVS
ANVSNSLFHGRTLPATVADALRDSGLNPSQLELELTESIAMRDVEASVTMLEGLRTMGVR
LSIDDFGTGYSSLSYLQRFPLSRLKIDQSFVRDLLTNENNVKITRAIIAMAHSLNLSVLA
EGVETEGQLARLREEGCDEVQGYLFSRPVCAEEFETLLRGDADARTAA
>NIDE2629_HK_Classic|Candidatus Nitrospira defluvii
LMHPLVLVVLVAIALPSGLLIHVFQPHVIWVNLPLHSTMEALGGLAAILTGLVLLARKVE
WDDERLQGIASGLLGMGILEGFHALSSPDHGFVLLRSAASLLGGVAFSFVWHPPRLIGKR
AKALMPYLIGGGTIAFGLLVVTMPHRLPRFTEQAQFVPMALAVNGLAACLFFAGAAGFWI
ESTRTGRLEHQLLGTLAILFGLAETMFLFSAPWQSDWWIWHGVRFAGYLMALIYVSRGYV
RMVDDTRAALGEANRSARRLGAEYAVTRVMTETVTLQNVGHAVLQAIGETLEWELGMFWE
LDQQGQVLRFVDLWHIPKLDAEEFVHDSRGRTFARGQGLVGRTWAAGKPLWIPDVVVDPL
FRRTTLAEKAGLHGAFAFPVQKGQEIYGVMEFFFRAIREPDQDVLDMVGNLGIRLGLYID
RMRTEEELRRTEARLAEEQRLAEVARVLGDIGHDLKNLLMPIMSGAQLLESEVRDCFEKL
PEPALRSMKPSQDIAQELIEMIRRSSERIHERVKEIADSVKGLTRPLQFAPCRVADVVAG
VIDTLRVLADERQVALRTDGLDDLPVIRADEHRLFNALYNLVNNAIPEVPPVGSVTVRGR
TEPGGSRIVLSVIDTGKGMSPEVRDSLFTYRAISSKAGGTGLGTKIVKDVVDAHGGTISV
ESEEGKGTAFHITLLVDGPPGDAAPKT
>NIDE2650_PP_HPt|Candidatus Nitrospira defluvii
VSTEPEQTEDDFQKELIELFGQEAQEWLIQIHSALTELESQPDTDRHAQLVDAVVRGITS
LGGSAATVNLPDVERATFALLPFIDTLKDRTTATKQDFGTVREQFCLVIASVTMATGITL
DLGPVQDTPLQPEPAIDFLTLLNALRMLQDEQVAKGVASRSLIPQVMHRLEQEARQGESR
IQTAAFQQLLGELQNTDARCLDSLREALPGIAHNLSRLRVEGVTGLEPNNVLGTCMQQIE
QLQGMAKQVNATPLVTFLTGLQSFLALIVQRRIVIASQRVEAVEGRILAVMTTIEDWITA
GQQERDLMSRLLPAA
>NIDE2651_RR_unclassified|Candidatus Nitrospira defluvii
MPKILIADDSIAVRKVAERLLTEAGMGVTLAANGSEALALLSKDRPDLIVSDVIMPDKSG
YEVCAYIRGQANLADLPVLLISGIVNEEVSRQAESCKADGVLKKPFQGSSLKDRVLDLLT
KRPQKPAPIPEMPQPQTTVESSFVAEVCAVPAMPVPEEIAAPHVEAQEHRPSLEPITISP
EEPHAIPAMMTRDAMEDAAPAFHAAEPAPPAHDHEHHQAILAERDTRISELEAQLDEERR
RSLEQTQQIAHIQRALDEQHEQVAALSSHTQTLDQSLADERAQRTALAEQLEEVSKQMLR
IGELETALADEQHRAQQLSQQVSEGVRHAARIAELEAHLEAEREAANQLVQQITGLEQVE
TRVHELETTLAAEREQAELQRRERVELQHSADKVPALEEAGAKAQAQIAELDAALSAERE
AAAALLVQVKQLEAAAQRVGELDLALVSEQERSMQLEKRAMEAEHMAEQSTRRFEDMARK
LGEIAGLASQLGNGKR
>NIDE2654_HK_CheA|Candidatus Nitrospira defluvii
MSADFDRDQLLDIFVAEAGDDMGRFWKALHPDGKAHPEPADVAEFHTVGHKLKGAALLYG
FPGLGQLGALLEDTLERVQEIPAARWPEAMQLMREIAASFRGQVEQIGRGGGEEASVVEG
FVRRHSDLLPAVSSDSSAASVQRFDQPADEYLIPVLDQEVLSYFSPEAEEYLSTIQTLLQ
RLESDLANADTIHQLYRVAHTLKGSAYTVGFEVVGDVAHPIESCMIAVREGVVTVAPHWI
AVLRKAVDVIRSLMARDAQSLARLRQEVPRIRTMLGELGQGVSQGEPGAAATALSRPEET
SIQESVPAVPSDHDSVGHSMGEADTGELSEAYLIPALDSEVMSYFAPEAQEYLESLEADL
LRVDKDAGNPDTIHQLFRTAHTLKGSAYTVGFQAIGDLTHHIEDFMGAVREGQLELLPGH
TDVLLRAIDVIRALMRRDLSMVGRTRQRFSNSLQELKRLGETQSAPDQNHPLVSSIADGA
SVEEIREAEGQESAKGVDGKTGEEREVIRVSRDRLERLLNLVGELVIDRGRLEQRLRTLD
QLATQVLANKNRLTDAVRTFEDKHTFSFQPSPASSGEDTPQAYPGVSDFGSLEFDKYDDF
NILARRISEVTADITESMSQLSGSIHRAQDDMGSLQQLTLGMRDEIARARMVPIGTPFTR
FRRAAREMARATGKEVNLVTSGEHTEIDTGVVERLVDPLVHLVRNAVYHGIEPAGVRRSQ
GKPAAGTVYLHAAHRGNSVLIEVEDDGAGLDIAKIKAKAVKLGLVRADVADSLPESEVIK
FIFLPGFSTAEAVGDQAGRGVGMDVVKRVIETMNGHIEVESVYGQGTKFTMHLPLTLLIA
TALLVRVGKERYAIPLPSVREVTMSTASTIQQMGDRSVLQIGDEAIEVYPLGSLIRRDAG
TIDGATPVVVVRTSTGALGCAVDELLGRQEIVIKSLGGLKPYERSVFGGATIDPEGRVVL
VLDVSRLTTREYHEAMSVIQNPGSSPMLEGPAQPPSPQISDRQLPLLLIDDSLSIRKFVG
RMLESAGYTVETATDGEEGCRKALVQQYQLIITDLEMPKLNGFEVIQALRARPQTQATPI
LVMTTRAGEKHRQMAVSVGASGYIAKPVEERALIQEVRKWTGRESVVKK
>NIDE2657_RR_CheY|Candidatus Nitrospira defluvii
MSKIVVVDDSYAELQLIEGYLKSANHTVVSYPNTDKLEDKLALDKPDLIVLDVVMPGRNG
FQACRDLKSDERFKGIPIVLCTSKGQESDKFWGQQQGANGYVVKPFKAEDLVAAVKRALN
>NIDE2716_RR_NarL|Candidatus Nitrospira defluvii
MSRIVEIQTTTVVAIVTNNYLLRLGLQKIVDDAKWIRLVGQTAHAGNLDEILTSEQPHIV
ILDTEIGGAAPDLIQQIKRVAPGVKTILLSGFDDTECTRQALASGVDGIVLKVQPSAVLI
ATITYLADSGGEVVLPIGNRPTPLKLSHTPALSTAPLPPPAPTKWSDGLTEREREVVRLI
SEGLSNKDIADRLCISSITVRHHLTSIFDKLGVSNRQKLLIRAHQQGLVGSPALA
>NIDE2816_RR_RpfG|Candidatus Nitrospira defluvii
VVFVDDAPEILKHLQRTLAPMQAEWAMEFYPSATAALAAIREAPCDVVVSDMTMPGMDGA
QFLGEVRKVCPQAIRIVLSGDQSPANYLRSASVAHRFLQKPFDVATLKATIEKAEALRDV
LANPALRSLANEIKTLPSLPSIYQELMKEMQAPQASLKKASRIVAKDLGMVTKILQLVNS
AFFGLRTHVSDPEQAVALLGFDTIKSLVLSSQVFAQFDQAQLPSFSLDELWRHAMLAGSC
ARRIAKEAGASQQVTDEAFTAALLHDVGVLVLVANKPDEYARVLELIRTKQMPDWEAERQ
VFGADHAHVGAYLLGIWGLGDGIVEAVAYHHHPDDYKGSGFCAVTAVHVANAMAEAQALP
VENPIEVPGLDQQYLAREQFQSQLPRWRELCIAA
>NIDE3050_HK_Classic|Candidatus Nitrospira defluvii
VAIAENEALWSSTCDPSPRGRAIVSLIAVSIGVIFFLDAMTPLGVPVWVLYLIPLTLTYQ
APVTWIPYLTAGVCATLTLLCLALSDPMTSMPSWMPLMNRAAALGMFAVIAHLIVQYRGA
TERLIQTAALDAEHKALQLKEGLLLKNAQDVQDLYDHAPCGYHSLNSQGMFVGINQTELD
WLGYQKDEVVGIMRFQDLLTPESVELFHQQFPRFIERGVVRDLEFEVRCKDGTLLPILLS
ATAIKDPDGRFIASRSTLVDITERRKADAALRQSHQTLEVLVKERTAALEDTNQRLEQEL
AQRNLIHQALIASESRFRELIESLPLPIWTCLPDGTCDYLSPQWMNYTGRSADEPFSTGC
LQHVHPEDRPRITEQWRDAVARTQPLDAELRFQRADGLYRWFHAHAAPILDRDGRVLKWV
GTYTDTHDRKQGQEVQARLAAIVESSSDAVISKSLDGRILTWNKSAELMFGYSGEDIIGQ
SISLLIPPDRQLEETSLIELIKTGTRVQQYETIRKRKDGSSIQVSLTVSPIVDANGLVNA
VSTIARDITARKQIEEMMTQQRRLIELSYEPIFAWELDQGIVEWNRGCEQLYGYTRSEAL
GHSSNLLLQSRLPAPLSTIQAELERTGGWTGEIHHRTKDGRDVLVASRWGLLNTNGRSLV
LETNRDITQLRQSETMILKKNKDLETLLYVTSHDLKEPLRAIESFSVLIQERYANRLDEK
GQDFLRRIVRATQRLDQLLTDILDLSRAQRMDPPVDDIDAEQLMHEVLRRLERRIKETGA
RITIRSPLPRLRVNTTWAIQGIYNLVANALKFASAGQAPDVEIAPHSGMDLEGNELIGLV
VRDRGPGVAPEQRDRIFELFRRAVGREIEGTGAGLAIVRQVAERHGGRAWVEPREGGGSE
FFITFGVNQSSPRKV
>NIDE3051_RR_CheY|Candidatus Nitrospira defluvii
MTMRPFDILIAEDNEDDILLIREAFETVNMANRVAVVRDGEEALAYLRGEGPFSQCPFPG
LVLLDINMPKKTGLEVLAEIKSDPRFRPLPVVMLTVSEREEDIVRSYEQGACSYIRKPVT
FSRFLSVVKEFELYWTLVSRVPTLKR
>NIDE3052_HK_Hybrid|Candidatus Nitrospira defluvii
MHVLLIEDNEDDAELIQQALCERSTEAVTINWADRLQTGIQKLTECPVDAVLVDLSLPDS
QGLETLDRVRAHAHDAPVIVLTGLDNDVVAEKSLLHGAQDYLVKGRLTGDALRRAIRYAM
GRHRVEQALRKSEERFHLTCLATRDGIWDWEITSGVTWFNEAHQSVYGPAPENLRRGHIP
WAEQIHPEDQAAVLANLAQVLQSDQNLWTAEYRFRRADGTYAYVIDHGYVLRDHEDHPYR
MIGAKADITERRQAETMHAVQLAVGLALEESASLSEAIPKILRTMCELQSWTLGALWLVH
SQDKTLHCNALWHQPGLPAENFARIYRGLTLRQGAGLAGRVWKTGDATLCPDVLKEADGP
ILQAAQDAHLHGGIAFPIHTEKEILGIMEFLTCERLRPSSPRLERASELGAMISQFLHRK
DLERQLRQAQKMEALGRMAGGIAHDFNNLLTIINSWAELLTGEPGQTTRTQRGMAQIREA
GNKATALTRQLLAFTRHQIVERQPLNLNDRVTDIVELMKRVIGEDIQLALTLDPALGRVK
ADPGQIEQVVMNLVVNARDAMPHGGRLDVETKSVSIAHSDPLWPNPLTPGPYVTLAVRDT
GCGMDADTVAHVFEPFFTTKELGKGTGLGLSTVYGIVRQSGGTVGIESEPGHGTTFTIYL
PCIDEDSDSPRPVAQPRNIIEQSETILLVEDNDMVRGLAQTVLVGQHHTVLAARTGEEAL
QLVRQRGGKISLLVTDMVMPGMGGIQLAAELRTLQPEINIILTSGYSDREGSLLEQLDAR
TTFLPKPYTPDSLTKTVNAALHPTLSKQT
>NIDE3088_RR_NtrC|Candidatus Nitrospira defluvii
VAKPKVFVLTDDQATVAAVRSAIESECEVFVAAWDRTAVVQIHEQAPLVMLLDLGASSDP
AVEDRVRVLQEIRQTGHAGKVIACTEQTERRLAVRAIQYGAYDVLSKPLDITLLTQLIRR
AAGVADLEREARGVMVRGGPEEFSGMLGTSASIHRIFDAIRKVSTNDAPILITGESGTGK
ELTARAIHERGLRRQGPFIPINCGAIPESLLESELFGYERGAFTGAVSQKKGKVEFAQGG
TLFLDEVGELPNALQVKLLRFLQDHTFERVGGHQPIEMNVRIIAATNVNLKEAIEKGTFR
EDLYYRLGVVHINVPPLRERGEDVSLMAMAFLRQAAAHYDKHLEGFTREALEAMRAYAWP
GNVRELSNRVGRAVVMAEGTHVTPADLDIPHEVARPDGNSISLKVNQQRIETDLIMKAFT
LSQGNLSRAAQELGISRSTLYRRLRQYGMDRTLDARRVLGVFPRASLSEH
>NIDE3091_RR_NarL|Candidatus Nitrospira defluvii
MRTTGTVRILVVDDHPSFRRGVKDILEEGFEGASMAECGNAQEMLDQVREQPYDLVVMDI
SMPGRSGPEVLKELKQLAPMLPVLILSMHPEDQYAIRMFKAGAAGYLTKASAPEELVHAA
KKVMAGGQYVSASVGEALALTVRTGVDKLAHERLSDREYEVLCLIASGQTVSDIAESIHL
SVTTISTYRARILDKMNLKNNAELTRYALQHGLVV
>NIDE3092_HK_Classic|Candidatus Nitrospira defluvii
VYSLARFSLLEMTECSAVLRQLGEQSSSIQDAASRAVDYLFRTLGNSETGARDCVLVRCF
KTVSYNRLNPMTQQRVREQLGGIAPSPDLKCFTLMATAGEEAEWNHVERSHRYRSIPMVS
ADFVKQFPMFSQLLHQFGLSSSVDVAPEGEWLVDLEEKTYNVFYVPDAVGSPYVPVQEGF
VLKYGVKSVLCFGGMLPSRDLFAVILFSRTPVPRDTAALCKSLALSLKTSLLACDEAVAS
EAGVDAHSSSASVAGATEQEAGLRHQSRLAAAEQLLRVYENAVRTQSAGIAQAKQALRER
ADALERSEQALNEQTRIVNSVLRSMGDGVVVTDAEGRLVVANPAVESILGFSPMHVPLTA
WAERYEFLHADTVTPFGQEEWPLARALRGEKIDWLEVYLRASQGMPGRWISINARPIKDE
AGVLSGTVMVFHDITWLKRAQDALFESEYRFRSLVEGARDIIFTLSADITITSLNPAFET
VTNWSRSQWMGEPLVALLHPDDAGFCQDVLQAILERGAPLTCSMQISTKQGGYVTGEFVG
TPQMRQGRVIGVLGIIRDVTERRRIEDALRVSEERLRSIVQSTKDAIVLVNALMKVAFWN
KGAEATFGYSAEEIIGQPVTTIIPERYHQELERNVQRVRLFERVQLTSRTLELHGRRKDG
GEFPLELSVTSWKGKSDLFFTIIMRDISERRSAEEELDRLHHHNQVVLNSAGEGIYGIDR
DGRLTFVNPAAAKMFDWEAEALIGQPFSALVHRPDFHEGVSSERPSPIVETIQGGEIREE
ADSRFWRKDGTSFPVEYVSTPIRERGDIVGAVVVFKDTTDRKRAEAQLQDSLRRLRKLSG
RMEGIREEERGRIARELHDELGVGLTCLKIDLSRLGGLLGERMVPRDRAKVDEKIRGMKE
QVDSTITSVQRIVAELRPGVLDDLGLVAAIEWQCRDFQRRTGVACHCTVSHEDLRVDPEH
ATAVFRICQEALTNVTRHAQATEVHVCLEDQGEGLLLQVSDNGRGIPSDRLADARSFGLL
GMRERAGLLGGDVQIETKEGSGTTIVLQLPR
>NIDE3162_HK_Classic|Candidatus Nitrospira defluvii
MRWLHDRSIGQKFFISFGVILSLLALSLTALLLYLSRINSYVDRHKRITVPAIVTAATMQ
RSAYEMNLTLHLFLEQITKADAADTLARLSRHAEQIRSSLDLYRSTHAARTHPILLGMLT
QHQRMDLADQEDRAIARIDLILQELSALWQTALTGPQRAGVAPSPVAKADGLIVELMNNL
DQLVAAHRDIDVEMKVEGDLLLQQARLIAFSLVAVLGLVITVIYVSVNRQIAKPLQRLSV
TADRVAHHDLTAQFESWPGRDEVGTLAASLSSMVTSLREQTAATARKTKELEAFTYSVAH
DLKGPLREIEGFSSLLEKQFADGGDAQTRHQIDVIRHSALRLTHMIDALLKYSRLEQQDL
PRQRFNVLEMITTLITDRFSGLQGPKPKIQVALPFADLYGEPVSIRQAIANLLDNAAKFS
RHASPPTIIIGGTRMEHERILWVQDNGIGFDPSHYDKIFGLFERLHSPQEYEGTGVGLAI
VKLVMDKHDGRVWVESAPGAGSTFYLAFPERAESVVDRPSSSPHPASA
>NIDE3163_RR_NtrC|Candidatus Nitrospira defluvii
MTMEHMRALIVDDEEFVRLVVEQALREEGCDTQTAGGGQEGLDRLRTASFDCVITDLRMP
GLDGRAILRWLKEHQPDVDVIVLTGHGDVKDAVAAMKDGAWDFLIKDTPFDGAAVKAAFA
RLRTVRELRRENLAARHGGYRQDAIVEGSSQAWRTVKTQIAHVAPSQAPVLIQGETGSGK
DVVARLLHAHSRRADGPFIAVNCGAVSRELLESELFGYEKGAFTGAAQAKPGLIAAADGG
SLFLDEIGEMPGPMQVSLLRFLDRKEYRPVGSTRTLQADVRIICATNRDIQELVLQGRFR
DDLLYRINTVTLHVPPLRERPEDLAVLADHILHHLRIPGTATRTLSPEALAHLATYRWPG
NVRELRNVIERMVLMSPNSGPITREEVLQVLPRAASASSPDDRSQLPLDEIERRHIQLVL
ESSGGNKTKAAQTLRIDYKTLLAKLKKYESGGEQER
>NIDE3228_RR_CheY|Candidatus Nitrospira defluvii
MEGYGKRVLIAEDEESVRRLLAVVLEEAGYTVHAVKDGMEALAEMKKRRFDAVVADYRMP
RLDGEQFLLLSRLMWPQTPTVLLSAEHTDLPVILKMQGACALVPKPFDSQGLLQTLQAAV
EAACSCCSPSSIPREGTNNTLSVSPS
>NIDE3244_HK_Classic|Candidatus Nitrospira defluvii
LSDLLSNLPIARKLFLASVIPALTVLLLSVLTYRSVTTFSDDEGQLNDIYYSQRLASEYL
RLVVDLETGFRGFVLTSQEHYLFPYRTAQDHVLNIGRTLEAQVSAYDDQRALITSVQKLV
RQFIDEKETLIEAVKAEHTEEARLYIEEGKGRTLMLTIRQDMGRFEHLAQTALNTKLAKL
AQDRDTMLMTILGGGLFALICMVAALHLIAHSITTPLERLATAVMATDTHPIPHVPVMTR
TDEIGNLSRVMHAMSSAIHSHIAALQLSEANLRKLNQDLAGSEAKYRSIVDHAPFGIFTT
RGMTLVFSNRYNSLLAGLDPSEEKDPDAVRRAIHPEDRERVIEEFAQAVTEGQPYETVFR
FLHADGTVRKVLSRRIPIRDHSGEVVMYQGFNVDITALDLMQSRLRRAERLATLGQVAAG
IAHEIRNPLVGIGSTTSLLLDDTDPTDARRPDLAVILQETKRLDRIVNQIIDYARPREIV
AFAFDMAQLVQEVMKVLDEPLTRKQATIRLSAPDAPYTIQADRDQLKQVLLNVLQNAIEA
SPSGGTTTVTLVQQARGVEPGLEVTVADRGTGISPTHLPHVFEPFFTSGKPQGTGLGLAI
CRNILEAHGGEIALDSEVGRGTTVRVWAPLRQQPLRMQEEEQHAGHDLRHG
>NIDE3245_RR_NtrC|Candidatus Nitrospira defluvii
MQATIYVTDDEPAIRSAIVKRLSRRHHTVTGFESGEDVIRAVTQHAPDLILLDLKMPGMG
GVETLRQLRPIAPQTLIIMLTAYGTVEDAVEAMRLGAYDFLIKSVDLSGVDPVVDRAIEF
LTLRHRVEFSLEDQNSAYALSNIDARSPAMQLLLGQVRDVAANAKSTVLLQGETGTGKEF
LARVIHCNSPRASGPFVAVNCTAIPKELFESELFGHERGAFTGAHQRKRGLLEKAEGGTL
FLDEIGDLDPAMQAKLLRVLQERTFRRVGGTEDLSVDFRLMTATNRDLKKDTARGSFRED
LFFRLNVVTFELPPLRVRTEDILPLSMQAMLRFGKEFGKEVIDIEPEAQELLQRYSYPGN
IRELQNIIERAMILCHDKTLTAGCLPRELREQAPHIAVAMAKGEHPSLRIEMVLGQQTLA
DIESALIEEVVRLSDHNKTLAAKHLGLTRFALDRRLKKQMDQD
>NIDE3246_HK_Classic|Candidatus Nitrospira defluvii
MAGKHKSWILPGIVGLTCGLFALDLFMPLGVAIGALYAGIVLLASFSPNPRLPLLTAACA
TGLLIVGAVAGPRLSSIPLWVGVTNASLGLVVVWISAMLLRQRHHAETRLRQAKDELEAR
VAARTRELADVNRTLLHEISEHVETEESLRASEHDLATSRQELRDLAARLLTAQEEERRR
ISRDLHDDINQRLAMLVVQAESLESSLPPSAGDCSKELRSIQDRLTELSDDVRHLAYQFH
PSILDDLGLTVALQRLVDECAARANLQGTFDVSPSPPTVPQTVATCLYRIAQESLANVMK
HARANKVIVSLTSTADAITLTVQDDGVGFDTQQLANGHRGLGLISMAERLRLVRGTVTID
SIPHQGTRLSIKVPHAEVPV
>NIDE3247_RR_NarL|Candidatus Nitrospira defluvii
MTTPPRVLLADDHTLVLEGFRRIVEQRCEVVGAVEDGRALLDAATRLRPDLILLDISMPL
LNGVDAARQLKKLLPDVKLIFVTMHADPAYVSEAFKAGASAYLLKRSAARELEQAIDSVL
KGQYFVTSLLTKDLVTTLSAGQVGLFAQRQELTPRQREVLQLIAEGRTIKEIASLLNISP
KTVEFHKAQIIFHLNLRTTAELTKYALAHGLTSA
>NIDE3254_RR_unclassified|Candidatus Nitrospira defluvii
MSVTKHKVFTILLVEDDAGDVDMFLRTVEHELPRHEDEQVTLVINATAEGALERLQQQPI
DLIIADVRLPGMSGIEFLRRVQDLNRRIPVIIVSWVHAIETVIDAMRHGAFDYIVKPYDT
MDLSARIHRAMRMSEILLQASPDEPAAPRIPFKNLVGVSPPIRNVMAMIEAIARVPSTTL
IIGETGTGKELIAKAIHERSLDSDGPFQVVDCTTFSEGTVESELFGHVRGAFTGAVADRT
GLIESGSHGTVFLDEIGDLPANLQAKLLRVLEAGEVRAVGSTQQRKVNVRFIAATNQDLA
EKVKRNEFRKDLFFRLNVMVIRVPPLRERTEDIPVLARHFIARYAKEFTKRVEDLHPSAV
TELVAYPWPGNVRELRNVMERAVMLAKGDRIGIADVAGMLAVPDERQREATEEDYLHLPY
AKAKEQVLEAFNRRYISTKLTIHQGNVTHAAQDAGLPRSYFHEIMRRYTKDEK
>NIDE3283_RR_PrrA|Candidatus Nitrospira defluvii
VKGLKVLIVDDEPLMRLSMLDALEGIGCEVMAAATGTEGLTILGTRQFDIVITDLRLPGA
DGLTILKACKERSPTTEVILITAHGSVDTAVGAIKLGAYDYITKPFQMDELLLIVERVGK
ILGLRRENLELKEVLEDRFSFGGILGRNHQMRALLEKIKLVAATDSPVSIVGERGTGKEL
VAHAIHLNSPRRDQPLIKVCCADLPEALLEAELFGHEKGAFPAALRQRRGRFELAHKGTL
LIHDIDAVSPTVQARVWRVLQERRFERVGGREPIEVDVRIVCASTDDLREMAHQGRFHKD
LSEQLTAVQIVVPPLRERREDVLVIAEHMLEARSAALGKSLDGFAQLSRDLLLHYSFPGN
VGELEQMVECAAALGREGESLQPWDLCGFQTCPYLGGSPQAGCGFCAEGLTAKVEKPESA
APATLATAREAFERDYIAAVLKQVDGSRTNAATILGLSRKALWDKCKRYGLSPAKGEAEE
KEE
>NIDE3284_HK_Classic|Candidatus Nitrospira defluvii
MLFWSRSHSLQRKIITAIVMVGLLPLCLSLVLTYIEERRALRETIGANFKEVAVEAARRI
EMQVTRGVNEAQQLAATPFLRTSVTESNRTYLDKDEKTVQSMIKAWQQRWRQRDKQSEFP
LFINRIVTNYLIRWHDIRKADYVGIFVTDNRGALVVSSIPQVEYYHGKAAWWQAVMKRGT
GKVFVSDIFFDPAFGTHVVNVSAPIIDDDQHVTIGAVTVLLRRDTLFHSVSEATVGQTGH
AMLFNSDGVPLICPVLAPEEHAVKPELVSAISASPAGWTTLANDSHGGQDSIVGFAPVRL
GAELTPDSLGGKRWVTFVRQDPAESYAPLSRLVVQVTVYGLGVFGVLLLTGLTVARRIAR
PIGLLHEGVQRIGSGRLDQQLDLKTGDEIEQLADAFNKMAANLRTSFEQIEQRMEDVRRL
EARYRDLIEHSPEMIYQLNKAGQFVHVNKTGLDKLGYSLEEMLQMRLWDLVPKGREAEVL
AYLERLVSQGRSTIETVFVAGDGHPIDVEIHATALFESGGGLVHSRAFVRDVTERRLLEA
QIHQYTTRLELAVNERTRQLVASQERYKALFDLVADSVFMVGEDGVIVAVNKREEQALGY
SEQQVVGSSILNVVEPLHHDEMRVLLEKIRAGERQVPTQEITVRDATGRETPVEMDLILV
RGSDHTWVMVQLRDITDRKRLERQMHTYQQELEAKVGERTREIEETKQYLENLLENANDV
IYTLDSEQCFTYVNSKVLAWGYAKEDLLGRPYLGLLSKRHRGRRLKSTLDIGVKQVYEVE
VLTKSGEPRSVMVSVSPLHGVEGEILGVLGIARDMTETKKLEQQIRNSEKLASVGKLAAG
VAHEINNPLGGILNCLYNMRKGTLSPSRQEEYLASMEDGLRRVQRIVRQLLDFSQQHNPE
LALADINQVVNRVLLLTDHLFVPHRVQLETALSPDIPELMIDRHMMEQVLMNLVLNAIQA
MRTGGVLTIRTSMDEAHCLVRIQDSGCGISSSVLPRIFDPFFTTKNEGEGTGLGLSVSLG
IVERHGGRIFVESEVGKGTTFTVSIPLATERHAIGRFS
>NIDE3387_RR_NtrC|Candidatus Nitrospira defluvii
MKAKVLIVDDDQDIVTMLQDRLDAGGYKTLTASDGLRGIELIEQESPNLVLLDLYLPRLK
GMDVLKRMAQNKQSEDIPVIVMTAAGTIPDAVEAMRHGAYDFLTKPLEKDHLLIVIQKAL
ERDSLKRQVAALQSDVQNRYATIVGDSPKIKTIIESARRAANSDASILLLGESGTGKELF
ARSIHQWSPRQSMPMVVINCVALTETLLENELFGHERGAFTGADRLQKGKLEMAEGGTVF
LDEIGDMPLPLQAKLLRVLQDKEFQRVGGTRSVSVNIRFVAATNKDLKQAVKAGQFREDL
FFRLNVVSFTLPPLRERSEDIVRLAEFFLKRHACEAKRPGVSLSQAARAALTHYPWPGNI
RELDNVLSRAVVLSPSDVIEPEFLALSPDDAAGKGSSEHGLSYLNLTYHESMEAHSAYII
ERALEKAAGNQTKAAEFLDLQRTYLARLIKQRKSTTDE
>NIDE3414_RR_unclassified|Candidatus Nitrospira defluvii
MEPASILIVEDEPVVAKDIQLSLQRLGYRVPATATSGEEAIRKADDMHPDLILMDIVLKG
KMDGVETALQIQRKQDVPVIYLTAYADDHTLERAKVTSPAGYMLKPYQAHELRPTIELAL
HRAQHERHMRERLRWIATTMRCIGDGIVTTDRGGRVAYMNPAAESLTGWSQDDAAGMGVT
ALLGFHEAGPGYESESPVQQAMTQVRIVAIEDVLLISKQGGRRAIRGSVAPVADDGGSVL
GAVLVFHETASGERALQASGQQGDRLWKMDARLGRPQGIINLCSWCKRVPDESGEWYDLA
TFIAERSAIQFNGGLCPECMDQCFPCDGRHK
>NIDE3415_HK_Classic|Candidatus Nitrospira defluvii
VALALIAGIGAIDWWLPLGLTITTLYVVPVLIASRIPHPRLTFWVAALASLVTILDMFDQ
PFFALTWVSAVNRAFALMVIWVTALLCLRRQRDEAELLRINEDIEQQVQERTADLAAANQ
ELEVLRAEAVSELVAIVKSSDDAIVGMTLNGMIQSWNRGAERVYGYRAEEVLGRPISVLC
PPNRLDEVPTMLDRIARGEHVRNVEMVQRRKQGERIDVSLTISPVKDADGCVMGASAIAR
DVTVKRRIEAALRESEARFRMMADTAPVMVWMAGPDTHITFINKRWLEFTGRTVQEEIGD
NWFTGIHADDLDRCRKSYLEAFKSEQPFFLEYRLRRHDGEYRWIMDTGVPLFDEEGRFGG
YIGTCMDLTERKDMEDQLRRMLKEKESLLREVHHRVKNNLQVISSLLNLQSASIKDPVVN
QLFRECQVRITSIALLHETLHRSHDLSRIKMGDYIRTLTGHLFRSYGVDPNVISLELNVD
DVEFDIDTGLTCGLIIDELVSNCLKHAFIDDSGGTVHIDLLDHVDGTFTLCVSDNGIGIP
KDGVLNNPDSLGLELVTLLAEKLDGSTELRSGAGTEWQIRFQQLQYSERV
>NIDE3461_RR_unclassified|Candidatus Nitrospira defluvii
MPQRILIADDEETFRESTVEILAEAGYACSAARDAAEAESLLENGYDLLLADVRMPGNAH
LEFLENVSRRHPELPVLVITGFPTVGTAIESFRLSIVDYLIKPVGVDDLKRAVERGLRRR
TLARAVKEAMTETAKVAGIFDQLGQSMREFGRGEPQVEWSAHEYIAQAMRHIAQLSTVVG
QTLEASRGSNPHAPTDLCALMPCPRLDRYEAAIQDAVEVMERTRSSFKSKEIGALRQRLE
TLLREGRRQR
>NIDE3462_HK_Classic|Candidatus Nitrospira defluvii
MNRAAHWVRHIQTLLSEGITGGRWYALCAVIMAATAVVDVFTPLGLADGAGYLVAVVVAG
MAPVQRFPYIVAAMSTGLILLGGYWSHSGGIPWIGVTNRAISIGAIWLIAWVVLQWRTAA
RSRAHDLSVRLRSILTHSQTNIFVKDLQGRYLEVNEQFLFLTGHSAAAVIGKTDSDLFPP
ETAALYREHDGQVIEAGAPMNFEETWVLNDGLRLYMVSKFPLRDEHGAIVAIGGIATDIT
ARLQAEAARSEAQERFDLVATATQTGIWDWDLLTNHMYYCPLWKASLGYQENEISNSPTE
WESRLHPDDNARAVALVDDYLSGRILSYELEHRLRHRDGSYRWIQTCALLQRDADGRPRR
MIGSHVDITERKRAEHALAQSESTLRSFFNSGAMMMGIVELLDGDIVHVSDNRRAASFFG
TTPESMQGKRASELGAPTDIIAHWIRYYEETERTKQPVRFEYVHSQRGSGVELCLSATVC
WIGTGPSGRSRYSYVVDDVTEARCLAEALGQTAERYHGLVTALAEGVLLHDEQGRIVACN
PSAEQILGLTADQLMGRTPVDPEWQAIHEDGSHFAPDQRPPVVTLRTGRPCSNVIMGLSR
PTGEWRWISINTQALRRPGEERPYAVVGSFHDITERRRAEQALLEVQDKLEHLVRERTAR
IHELESQRSQAEKLAALGHLAADIAHEVNNPLAGITNAFHLVKQGIGSDHRHYRFVELID
REIERLAIIVKKMYSLYQGVPATERQATNIDELLQDVATLVGHKLTSKRLRLRTDVVTRR
QVVDAPRSDLFQVLLNLVQNAIDASPADSEVGLSVAERDGQLRWSVTDRGTGIATDILPR
IFEPFFTTKSGAGWQGLGLGLSVSRGLVYAMGGRIEVETQPEHGSTFTVVHPLERSGPGE
GVCAPSALRKEQKDDDYAATHTHC
>NIDE3520_RR_NtrC|Candidatus Nitrospira defluvii
MGIAGKILIVDDEQDALENCRRILSRVPYDCLTECDPARALDVIQRERPGLILTDLRMPD
LDGIEVLAAAKRFDPSVQVVLLTAHATVQTAVTSMRYGAFDYITKPFTSADLVSVARRAF
GEDGAGPVAAAVGAHKLLETPEQARSGKRPGLSRVIGESPAMHSVFNLIEKVAPTHSNVL
VYGESGTGKELVARAIHDASLRAERPFIPVDCVSLPDTLLESELFGHEKGAFTGAHVSKP
GLFEVAAGGTVFLDEVSGMSQTLQSRLLRVLQERQMRRVGGIRFLDVDVRVIAASNQDLE
SACRRGEFREDLYYRLNVIPIVLPPLRTREGDILLLAQEFLRRFMKQQRLGLAFVPELDS
SATDLLCGYSWPGNVRELQNVIERAAVLADGPVITSAHLPDRLRECGGEDAASAEAGSFK
HAKQAAVTNFERNFLIDLLKRHDGHMGRAARESGVDRKTIERMVKKHGLRELF
>NIDE3521_HK_Classic|Candidatus Nitrospira defluvii
VTIRTIKGRIVLAIVLVGCIPLVIGLVLASMSGMRSLRDVIGGNFQAIAEQAADRLTMLV
QSEVQGVRLLASAPLRVRQPVEAANLSYQGDWADSQRLIQERAKEWEKGHDSAAGLLNSE
LSRFLLETKVRDGDKMVGLLITDRYGALVAASSEPDHYFLSQEPWWEALQAGGLDRVYVS
GLIPGQEGSFRSPEETIDIAVPILDDHQHAVIGAIKASYRFDSLFAMIKEIRIGQTGHAM
LFDAAGQPLVCPILPRRAHRIPSQLMAMIVSSNPGWGIAEDDGHGATDTVVGYAPVTGLS
LPDNSWHVFVRQQPEETYAPIRDQLRNLALIGVVMLGLLWAMGRYVAARIARPIQVLKSG
VEAISQGTYDGPLDIKTGDEFEELAVAVHRMADRLQSSRAELESLNAELVHRVEEKTAEI
TCQMRKLELSERLATLGKVASGIAHEINNPLGIILNRIECMEADAAQAGVPEQVGRDLVT
IRTQAERISRVTRSILTFSRGTVSMLKPLDLNCVARTCVAMAGERVAALAVRIDAQLAPE
VSPVMGDRDRLETVLLNLINNAIDAVTGCDGQGIITVSTARVPIDGDEWVRISVSDNGPG
VPTAILDRIFDPFFTTKPAGQGTGLGLFLSYGIVSDHRGRIEVRNNAVGAVFDVYLPAVA
FGNRVHEGASWGLQEKS
>NIDE3536_RR_CheY|Candidatus Nitrospira defluvii
MGMAWPFGLVADEKVCLGRVLVVDDEDSIRSLLRMTLAQAGYDVEEAEDGGRAVEVLNSG
DNPLMVDVIICDIRMPRINGVEAIAYFRAQYPSLPVIVLTGYHDEQLASSLRKQGVVECL
EKPAEREQILTSVAQAIAGRRISFYP
>NIDE3570_HK_Hybrid|Candidatus Nitrospira defluvii
MAVSLPAGSPRRSYPWLPVLIVGVTIVALVIGVVMLRSIEVRMVEATGENLTLASAEIAD
KLDRLLFERHADVRMMARAFSDRALDKKYINEYLQWMKETYAPVYLWLGVTDAHGRMVAA
TDSAVIGQDYSRSGWFDRVRQTGTVQVDEVEIHESNHKIESVAFTAPILSVGGQFLGAVT
TRIGLPMLEDVLIETVREIQQTDGSAGPFEYQFLTKAGVVFVDSAFSGIDRVNLTELGLP
SVLLSRSGKAGYVEEMHARRRVPVVTGYSQTKGYGDYSGLQWTILLRMDRDLILLPIRAM
MWKLGMAGVVVWLPMVGLLLWATGRLREQHRQAQQESEWARAAEAALLQSQERNRVIVDT
ALDAVISMDAGGIITDWNAQAVNIFGWEREEALGRRVSETVIPVRDREAHERGLRHFLDT
GQGALLNRRIEMMGSHRDGHEFPVEITISPARLGDAYIFSAFIRDITARKRTERQLASQY
AVTRVLAESRTLEEAGPKILQAICESLEWELGIFWRLDRQGSVLRCLDVWQSPALNAEEF
VLDTWQHTFTIGKGLPGRIWQAGEPTWIKDVVQEANFPRGGAAARVGLHGAFGFPVRVGT
EVEGVIELFRREIKQPDEQLLKMVADVGLKIGQFGERARAEDALRRTEAQLQQSQKMEAV
GRLAGGVAHDFNNMLTVIRGYSELVLSRLAPTDGFRKELEEVKKAADRASGLTGQLLAFS
RRQFIAPKVLDLNSVIHNMEGMLRRLLGEDIVELCTVLDPGLGQLKADPGQVEQVIMNLA
VNARDAMPNGGRLTVETSNVQFGQRRNRPPMGAEPGSYVALIVRDTGHGMDEDTQSHVFE
PFFTTKEKGKGTGLGLSTVYGIVKQSGGCIEVESKPGRGATFKIYFPRVESAATETESVA
VGGDSVRGRETVLLVEDEPGVRRLVNETLRLHGYTVLEARHGIEALLTGAKHAGPIHLLL
TDVVMPQMSGPEVAEKLATVRPEVKVLYMSGYPDHPAFSKGGIDTEHSFLQKPFTPTTLA
QKVREVLDGSKVA
>NIDE3585_RR_CheY|Candidatus Nitrospira defluvii
MGEFKSGFFMSESACNGRVLVVDDEPDIRKVVRMTLQKAGYEVIEAENGEKAIEAINTGE
NRLLLDVLICDIRMPKINGVEAIAYFQQEWPRVPIIVLTGFPDTDMATSFLRSGVVDYLV
KPVEGEKLRTAVARAMEQRELAQL
>NIDE3586_HK_Classic|Candidatus Nitrospira defluvii
MKLCSTRIAIIGAGKGGTALLDLLHQIPDVEIVGIADRDPTAPGLTRARDLNVLVAERVE
NLIQNHGVNLIMDVTGDPSMEPLIHTLKRPGAEVLSGAATRLLWKLVQHQSKLEAELFQA
DKLAGLGSFAAGIAHDINNPLQLILGLAENLEEEQDLAVVHEQARDITQAVKRTSAICRD
LTRYARRNGAGEEVMVNLNTKLDEALRIARYAVTLQDVTVVKRYAEEASVMGNPDELLHV
FVNLITNAVQAITDHGTLTLQTTVGPDGLVSASVSDTGCGIPKEALSKIFEPLYTTKPPG
KGTGLGLYNVMSVISKMDGHICVESDVGVGTTFRIEFPQVQPTISCAPL
>NIDE3587_HK_Classic|Candidatus Nitrospira defluvii
MRATMTNPSGSFSNALGWGLKRKLIVSMLMVGVVPLLLGLSLAFLQGSKEIQVVSGESFQ
ALATEAARKLDLLVAEEVARTSRIAVHPDIVRALEHRRDALHTSDQNAALPTLVQQRARW
AAKDPAAVKAITGNSTALLLQSFYAGSQSEPDQLLPQVVRAATKKLFITDVQGNLFAALT
TKPGFSHADSPWWKGSYNRGVGQLYIEDLHFDEQANAYVFSISLPVMDSLRYEVVGVVHR
VIDAKEFFSPSTHPIRFGKTGHVMLIDSRGMVLSCPILPTGVQLSGATLIPQVTVRQPGW
VTADSDGHGGQGTAIIGFAPLPETSRATNGALESGAWHTFVWQSSDELFAPIRHLMMWMM
ILAGIALGLLATLGYFAASRIVTPVRRLQEAARLIGRGELQEPIQIHTGDELEELAVEFN
RMNTQLEAAFAGLSTQVEEKTQEVQYLQKSTDQVLDAVPTPIIMIDQQGLVQYMNRASRD
ALQTQEQNWSSRPLFDLLPLDDDHLQTLRRDLRLVEENKPIAPPRPDQEPALKEARDPLN
QTLSQASPSTRRELRIGSHLYHYEWFPLESRSGAGKRFGLVLRDTTDESRLQDQLIQAEK
SGSLDVLTAGIGHELNNPLFGILGLGEAIQEEADLARAKGYAQDIVGHGRKMAAIIRDFT
GVAARESKSQRVPVDVTAQLEQALAIVQTSHDCLGLNVQKHYVAVSPVTALPDQLRLAFI
NILTNAIQAMSGRGDLWLTTEEQDDLITITIRDNGPGIPKHHLGKVFDPFYTTKGQGEGS
GLGLTVAQRLVKKFGGEIRLESPEGQGTTCVITLPADKAGVRKEQPCVSS
>NIDE3593_HK_Hybrid|Candidatus Nitrospira defluvii
MDRPSHTDPAPDLHTLQVQVLYRNMPTGVAASAINAAVLAAVEWSVVPHPPLLLWVIGLW
IVAAARALLILSYRRARPTSWSSADWHRWMLVTTSMAGFGWGSSVYFLTLNIPLPYELVQ
LFVLGGMTAGAVSVLSVSFPLFLWYAVPLTLPILGHLFLSEHEFHLIMGGMGVLFLLAIV
HSAWNFNRVLLSSMRLQLEKVALARSLTARTEAVERLNQEITKEIHDRRVIEEQLRTAQT
DLGQRITERTADLAQANARLQNEVLEHRRTEGARLSSEKRFNYLTDNLNQGVWFAQANPP
QVLYVNPAFERIWGLPAARFYENPKLWRDFIHPDHRQVVSEVYDAEIANPTGRDLHLLYR
IIRPDGQVRWIHDRMVIHHTATGEVDNLSGITEDITEARELEDQLRQAQKMEAVGRLAGG
VAHDFNNVMTVILGYSAVLLQELSQNSSARYFVQEIQRAGERCAALTGQLLAFSRKQMLH
PVSLDLHRVIRDLMALLKSLIGEHISIVLQLDPLPLWVKADAVQLEQVLLNLAVNARDAM
PHGGTLTIDTRQVSREEVWGTDHDSRTARTYVRLRVHDTGTGIDPATKAKIFEPFFTTKP
PGRGTGLGLSTVYGIVHQSGGTITVESAVGQGTTMSVFLPEVVPPHTALPPVQSEPAHTT
GTEIILLVEDEPAVRLLTQHILRTHGYTVHEAEDGFQALDLIRRNALHIDLLLTDLVMPG
MNGKELAMRLRSHFAELKVLYMSGYSDNPPVTGDETQGHTTFLQKPFSPEDLIRMVREIL
HSVSPA
>NIDE3607_RR_unclassified|Candidatus Nitrospira defluvii
MLFPQTQLLLVDDSPLNLKILLEFLPQPDYRCTTAQGGLQAWEMLEAQPDRFHAVLLDRI
MPEMDGMEVLRKMKQHPVLSQIPVIMQTAASTHQQTLEGLQAGAYYYLAKPFEKATLQAI
VDAAVRDHISYLEVRQDLRRTTTTMHLLDSGTFRFKTPEQAKNLAMLLAHAYPDANRVVT
GILELTLNAIEHGNLNIGYKEKSRLIEEEQLDSEIERRLSDPLYSSREATAQFVRRPDTL
SLHISDQGKGFEWRKYLNFDPDRAFDTHGRGIAMANKLSFDTIEYRGNGNQVIAVLQLGT
VAQELVA
>NIDE3753_HK_Hybrid|Candidatus Nitrospira defluvii
MAVSTPRSNTPSYDPQVLLDSQPVTVNVIDPADHSVQFQNRTSREVFGDMAGSRCHAKIA
GKAAPCEFCRMPEALARGGVVSEEVDMPDGRRLQIHWAKAPTTDGRIHVIETIVDVTKRK
QDEQSLRQSQKMEALGRLAAGIAHDFNNLLMVVIGHAQRVAQQLGSHPCHHEVEMIGQAG
SRAAALTKKLLTFSRRQVLEQRDVPLNTLIRDMEDILRRLIGEQIQTVIVLDSKAGHVLG
DPVQIEQVLLNLALNARDSMAEGGILTIETGNADLDEAYVRAHPGAVPGPYVKLVVEDTG
CGIDAETLAHIFEPFFSTKEFGKGTGLGLATVYGIVKESRGYIDVTSQPGRGSRFTVMWP
RVLTQTGEAEPVAASRAVPAACATILLVEDDEGIRRLVSAVLRDQGYEVLAATDGVEALQ
MLQLRKGGCDLLITDVILPRMKAAVLAQGARTMFPNIKVLYISGYSGDMLVSHGVDAQAA
YLQKPFLPQAIIEKVAELLSPTRS
>NIDE3940_RR_CheY|Candidatus Nitrospira defluvii
LRCVVPMVIYSEGSKVESRTPAVLLVVEDDKDMRSLLCDELWGEGYQLREASNGDEGLAA
VMRAAPDLIVTDLKMPAGGFDYVHRLRRCVPGCPIIVMTAFGDAQTKDEAMKSGATAYFD
KPVRLSELKATVKQLLQHPGGRSEDGLFH
>NIDE3941_HK_Classic|Candidatus Nitrospira defluvii
VQPLHQKSPLFECGLPLLLTVGIFVLDLSAPAGIDLWLLYAIPFTLIAASSLGQVRLYGM
GLVALLAFIGPLVSSAGSLSPFTGLNRLLGIGIMGTVAALVARRRSSPGSPGLSSQAFTT
ARAERHQPEAIGASDAEARARAEAAVVGAVDGQRRAEAELHQDKLRFEGIVHSAMDAIIT
VDEAHKIVLFNQAAEKMFQWGAEEVLGRPLDRLLPERFRSAHDEHIREFGRSGITTRQMG
ALGMVMGVRANGEEFPIEAAISQIGVEGTRYYTVILRDITERIRLEQELAEREALLRAII
ETEPECVKLLNLDGTIRTINAAGLAMIEATSGADVIGRDACRLVTDEFRSVYRELVGKAG
RGEAGRLEFEMVGLLGTHRWLDTHVVPLRSADGTVTAVLGVTRDVTEWKKTEALLRQSED
RYRRLLAVLPDAILVNREGRIIFTNEQGVRLFGARSGEEILGKSLYDLAHPDYHELIGER
IRHLLRPGNTVPEVEEKIVRLDGVSVDVAVRAARFQDEEGFGILVVLRDISMRKAAEQKL
RESEERLQSLLGAMEDVIWSSSLDLSTMFYVSPSVMEIYGRPTDAFLARPSLWLEAVHPD
DRVIAEQARQALSTMGEFDVEYRIVRLDGDLRWLHDRGRVIKDAEGRPLRIDGIASDITE
RKRLQAQLRRTERVAELGTVASGMAHEIGTPMNVILGRAEYLMERTKEEPVRKGLQTIVS
QVERITRVMNQLLAFARRRPVEHRALDLRQTIEDNLEIFQERLSHSNISVETSFADACPL
VHADADQMSQVLINLVMNAIHAMPGGGLLKLALTPDRGMVRLTVADTGHGMPRDVIAKVF
DPFFTTKEFGKGTGLGLTVVKGIIEEHSGTIEVESEPERGTTFTICLPIDKS
>NIDE3942_RR_NtrC|Candidatus Nitrospira defluvii
MTEEWGAVLVVDDDADMRSLLCDVLQGRGHQCTGVGSGDDALQQLSEEDYAVVLTDLRMK
GMLGTELLAEVKQRYPDIGVILMTAFGSVETAVEAIRHGASDYLTKPVKTEELVRVVERA
IREAALRREVSRLRKEVHKEYSFHQILGKSKPMQAVFDLIRRVADSPTNVLITGESGTGK
ELVAKAIHYNSDRRDAPFVPVNCAAIPEQLLESELFGHMRGSFTDAKMDKRGLFEEAQKG
TLFLDEISELPLMLQAKLLRAIQEREIRRVGATKSIPVDVRIIAATNLNLAEEVKNKRFR
EDFYYRLNVIELRLPPLRERREDIPILVDAFLKKCADSRGKQVKGLSESALAMLADYAWP
GNVRELENVIERAVTLSHGDMIGADDLPVQVQGSRGDRRILDEAAERTLPLHEVEKEYIV
KILEKTGGNKYQAAHVLGIDRKTLYRKLAEIEGKPHSDA
>NIDE3963_HK_Hybrid|Candidatus Nitrospira defluvii
VSVPPSSSDLDQTGRHLNIRGLGRLLDHSRTRTIFLQSLVAGILSYELLVSNETIFGHRV
SLMVAAGLILISCGIMLLPRTLLESTWFPGALISINTLFVTGTIYLSGTASSELYLTYFL
LLLIASSAPSLRQLLGLSTVICAGYGVLVYEHAMQSGGLEVGHLLGIPVLLIMSVFYGLT
LETVATERRRNRLLQENVQGLKQSGQVLEERRTQLETRVQGLKQGLSRANQEIRQGMVER
TGLERQLREAQKFEAVGRLASKLANEFNQVLAVIGSQTGIIVSKLKPDDPLQRPVEEIFR
SGERAATLTAQLLALHVQETAIRDTLSLSPAIESMRDTFETLLPGRIDLRLANESIPVLV
EIGHDRLEQVLLHLVANARDAMSKTGRVEVTLEVVTGELLPAEQLEKNPRKRMARIAVSD
NGGGMNLDVQAQMFEPFFSTKDTHAGLGLTLVYGIVRQYGGTVEVQSQPGQGTTVRVYFP
LVERNGVVRDTRVFGGALSKGAETVLLVEEDEITRKLASSTLQCHRYHVLEAGSAVEALL
VAQQHPGPIHLTVSHLSMPEISGRELAKRLVLQHPKMKALFVSGFSDDTIASHRVNKKYF
LQQPYRQHDLAGKIRELLDV
>NIDE3982_RR_NarL|Candidatus Nitrospira defluvii
MSKARVLLADDHSLVLEGFRRILDDQCELVGMVEDGRALLEAVDRVHPDIVILDVSMPLL
NGIDAATQLKKTHPSIKVIFVTMHADADYVRSAFEAGASGYLLKRSAVDELEQAIRAVWA
GHTYITPLIAKDLLDVLLTLGAGQAQQRKTLTFRQREVLQLLAEGRTAKDIALRLKISTR
TVEFHKAQLMEQLNLHTTAELIKYALTHGFIASS
>NIDE3983_HK_Classic|Candidatus Nitrospira defluvii
VTTQPSHRLLLFAIVVLGLGLYTLDLYLPLGIGNGVLYGGLVVLSLALPDRTTPILVASI
CSVLALSDVFLGVTLPNVPLWMGLSNRMFSLTAIWFPVIYAFQRRKIEEALRSAHSELEV
RVGERTRELALVNQALVEEIGERMETERSLRESESSLKVSQEELQHSREELRALAGQLLT
AQEGERRRIARDLHDDVNQRLAMLAMDLRRIEKGEAGDLAAVEGVVRSITRRLTTVSDDV
RQMAYRFHPSILDDLGLVKAVRRLVDDFSATTKIEAVYVHHDAVSPVPTELATCVYRIAQ
ESLNNVARHAQATEVEVELICDDEVITLSVRDNGVGFDSQQASQGLGRLGLLSMKERVRL
VRGTLTVSTAPGRGTHLEVCVPLPGGAYV
>NIDE4086_RR_FrzZ|Candidatus Nitrospira defluvii
VALSLLIQTHKRDTMMSTLLVIDDDRLHCDLLQMALARHGYQVSIATGGREGVALFRQLR
PLVTLLDLRMPEMDGLAVLKEIRTHDPRAGVIMLGGGATEELENRARELRVTDFLRKGLS
LDVLIGAVHRVAQQARRQASSEQARAGEEADQLPDEHILVVDDDVMARDLLVRFLGLRGY
HVRAAPDGREALRLIGESVPDLLILDLAMPEMNGVEVLRALAARDYAGRTIILSGHHNDS
LLAEAWALGPQEVLDKPIDLERALMAIQLVMVCREC
>NIDE4197_RR_PleD|Candidatus Nitrospira defluvii
MSGSEQNRRILLLHSDPLEIERLTAGLNRSGFTVVAADAGRLAMHELVHDPPCLVLAAEG
THGRSADTLARDLRADPFLGRLPLIMLVRDIRVNDLDWATLGVDDYIAVPYRPDEVPQRV
RLCLSRLERSLDANPLTRLPGNSTILHETTARIESRQPFALAYLDIDNFKSFNDRYGYAR
GDEVLVVTCRILTTVVSELTGTDGFVGHVGGDDFVFMSAPSSIDAICQTLIKRFDLVIPD
FYDPEDRQAGFIDSVDRRGNHERFPIMSLSIAVVTNEHRVISHPGDVSKIASELKKVAKS
RPGSVYVKDGRKTDSADSASESTC
>NIDE4240_HK_Hybrid|Candidatus Nitrospira defluvii
MSSSQSFPDREPPSTSPLFKPIDSARDSSIALQRVTLLYEAMPAALVAGLGCALALIAVN
WPVVPHDRLLAWLLYHLVLAAGRYGLARKFTATRPGPANIERWDRAFLAGTTLAGLGWGA
SALLLLPESSPAHQVFLAFVLAGITAGAASTLAARFDAFLSFSLPILTPLILRLFALDHE
QALPMAICTLLFSLLMVYTAYRTSNTVLETLRLKYHNAQLVDQLTGQLQEGEQMELLLTV
KTEHHRFIMEYAQDIIYRTDRSGRFTFINPAVIRLLGYHETEMLGHRALDFVHPDYRRPT
ERFYLRQFLRKTASTYCEFPLVTHTQQTLWVGQNVQLLQRDEEVIGFQAVVRDISVRKQT
EEALRVSQERYRALFESSPEMLLTVDAQGTLLTVNTTTAAELGYEADELIGQPVARIVHP
DDHGSMEKHFADSLRRPGEVLRWNFRKLRKDGSLLWVREAARAVRNSDGQFDIIIVCENV
TEQKGIEDALTQTRQLLESIVEHIPHMVFLKDAQELRFVQFNKAGEDLIGLPREALLGKN
DFDFFPLEQAEFFTARDREVLTGGTMMDIPAEPIQTKDHGLRWLHTKKLPLYDQAGMPRY
LLGISEDITDRKQREEAERLRLGKLETQQAVLHELAEDPAIHSGHPQQAFPVITEYAVST
FAVERAGIWLFDEHQSALILQDLFEATPKHHLQGTTLSTGEYPAYLHALETEPYSLAAHD
AQTDPRTKELTPSYLTPLGIVAMLDAPIRRHGRVVGVLCLEHIGPARVWTTEEQTFAASL
AAMATLTLEASDRRQAQEALEHHVRERTGELRRTTAHLQTIIEESPLAMIELDQAGLVTT
WNAAATALFGWTKDEVLGKELPYVPPGQEEVSEELWTAVMSGAAPRNLELRRQKNDGTLV
DVNMWGSLLQGPAGQAVGSIGFFVDITKHKQLEDQLRQAHKMEGIGRLAGGVAHDFNNLL
TVINGCATLVLDQVRAEDPLRRSLTEILTAGQRAAALTRQLLAFSRRQVLTFQVFDLNEA
LSSISSMIERLIGEDISLVRNLDSRPCTIRADRGQIDQVVLNLAVNAKDAMPTGGTLTMA
TQVLLITPDSPVPHPALLPGAYAHLSIRDSGQGMDRTTLSHIFEPFFTTKEEGKGTGLGL
ATVYGIVKQSQGFIFADSRPGEGSTFDLYFPLVEAPPLAAAPALPSRPHCGRETILLVED
QHAVRLLLTQALSDYGYTLLEASSGQEALRLVAAARTPIHILLTDVVMPQMTGPALAEHL
RRQWPGLRVLFMSGYAEGSVLPTFLAEPGTGFIQKPFLPTELAQKLRELLDPAK
>NIDE4271_RR_NtrC|Candidatus Nitrospira defluvii
MTQGAHILVVDDEVNIRGALVTLLEKKGHRVRGAGTGEEALEELEAAPADLVMTDLKMPG
IGGMEFLRRLKAKWPETEVVVMTAYGSIDTAVEAMRCGAYDYLTKPIDRERFPIVVEKAL
DRHALATENKQLKSRLDTRTRFDQMVGDSEPMRRVYNMVEMVAESDVTVLLTGESGTGKE
LVARAIHHRSARANGPFITLNCGALPENLFESELFGYDKGAFTGAMATKLGRFELAHEGT
LLLDEVGELSLKSQVDFLRVLETKEFRRLGGTKVIKVDTRIIAATNRNLEAAVKQGDFRE
DLYYRLNVVPIHLPPLRERAEDIPLLVNRFLIAFSTQYRREPKEVSRDAMRLLRLYAWPG
NIRQLRNLMERLVVTVKDAMIQPEHLPEEIQASKEDARTMLVTLGTPLEQIERDVIQRTL
AEVTNHREKAAKLLGISLRALQYKIKEYGIRA
>NIDE4272_HK_Classic|Candidatus Nitrospira defluvii
MFRPIPEAALLRRAPYRLIAAVLLILALVVSVILLFSLEQEKLLLQGVTQGKTVPTDLFP
ALWQSRRDLTLVALLVFLVSAIGITAVITFLHYDSTLRTLEEVKGLARNILESIPTGVLT
LNRSGIITAVNPSAEAVLKRASLDLLGHSYESVFTEGDTIRGALDAALRIHRHMSQKDLP
YESRDRTLHTIRVSTAELTGDDGRPAGVILQAQDVTEWLALERRVRVAEKLAALHTLSAG
VAHELRNPLSAIDLNLHLLEEEFKEQGGPAKQAAYYLRVLNAECRRLSVILDNFMKFARP
GSMGLHAVDLPALIEHIVALMRFEAEERKIQLEQRVSKDMSPVLGDETQISQVLVNIVVN
AFHAMPNGGRCSIATEERTEEGKRWVEIVVSDTGIGIEQEDLPRLFEPFYTTKSGGTGLG
LAIAYRIMQDHSGTIHVTSVPGNGTQVVMQFPVAVDHQQSVAVGS
