CEA/DSV/IBeB/SBVMe/LEMIRE - P2CS Database - Version 4.5
 

P2CS (Prokaryotic 2-Component Systems)

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Histidine Kinase Phophotransfer Response Regulator Incomplete HK Mispredicted TCS Mispredicted TCS Incomplete HK Response Regulator Phophotransfer Histidine Kinase Histidine Kinase Phophotransfer Response Regulator Incomplete HK Mispredicted TCS Mispredicted TCS Incomplete HK Response Regulator Phophotransfer Histidine Kinase

Classic Hybrid Unorthodox CheA CheA Unorthodox Hybrid Classic Classic Hybrid Unorthodox CheA CheA Unorthodox Hybrid Classic

NtrC Family PrrA Family OmpR Family NarL Family CyC-C Family LytTR Family Spo0A Family YesN Family CheB Family RpfG Family CheV Family RsbU Family AmiR/NasR Family PleD/VieA Family PleD Family VieA Family CheY Family CsrA Family YcbB Family PilB Family LysR Family ArsR Family FrzZ Family Sarp Family MerR Family BetR Family AlpA Family HxlR Family Xre Family CheC Family TrxB Family LmbE Family PglZ Family VieB Family HalX Family unclassified Family unclassified Family HalX Family VieB Family PglZ Family LmbE Family TrxB Family CheC Family Xre Family HxlR Family AlpA Family BetR Family MerR Family Sarp Family FrzZ Family ArsR Family LysR Family PilB Family YcbB Family CsrA Family CheY Family VieA Family PleD Family PleD/VieA Family AmiR/NasR Family RsbU Family CheV Family RpfG Family CheB Family YesN Family Spo0A Family LytTR Family CyC-C Family NarL Family OmpR Family PrrA Family NtrC Family NtrC Family PrrA Family OmpR Family NarL Family CyC-C Family LytTR Family Spo0A Family YesN Family CheB Family RpfG Family CheV Family RsbU Family AmiR/NasR Family PleD/VieA Family PleD Family VieA Family CheY Family CsrA Family YcbB Family PilB Family LysR Family ArsR Family FrzZ Family Sarp Family MerR Family BetR Family AlpA Family HxlR Family Xre Family CheC Family TrxB Family LmbE Family PglZ Family VieB Family HalX Family unclassified Family unclassified Family HalX Family VieB Family PglZ Family LmbE Family TrxB Family CheC Family Xre Family HxlR Family AlpA Family BetR Family MerR Family Sarp Family FrzZ Family ArsR Family LysR Family PilB Family YcbB Family CsrA Family CheY Family VieA Family PleD Family PleD/VieA Family AmiR/NasR Family RsbU Family CheV Family RpfG Family CheB Family YesN Family Spo0A Family LytTR Family CyC-C Family NarL Family OmpR Family PrrA Family NtrC Family
P2CS is an integrated and comprehensive database of two-component system (TCS) signal transduction proteins, which contains a compilation of the TCS genes within completely sequenced genomes and metagenomes. It provides detailed annotation of each TCS gene including sequence features, functional domains, as well as chromosomal localization. Data can be downloaded for analysis and users can validate and add annotation to predicted TCS genes.

The database can be browsed and searched with a user-friendly web interface.
Quick access :
All TCS present in the database can be retrieved with:
  • P2CS Search - Specific genome, gene or domain architecture search
  • P2CS Search - Blast search against all the P2CS database
  • P2CS Browse - Complete TCS annotation of each genome
  • P2CS Browse - Complete TCS annotation of each metagenome
  • P2CS Download - TCS data available for download in a variety of formats
A complete documentation and a How-To section are accessible via the Documentation menu

See the P2CS publications for further details.

P2CS: a two-component system resource for prokaryotic signal transduction researchBMC Genomics 2009, 10:315.
Abstract [ BMC ] [ PubMed ]  Full text [ PDF ] [ HTML ]

P2CS: a database of prokaryotic two-component systemsNucleic Acids Research
2011, 39(suppl 1): D771-D776.
Abstract [ NAR ] [ PubMed ]  Full text [ PDF ] [ HTML ]

P2CS: updates of the prokaryotic two-component systems databaseNucleic Acids Research
2015, 43(D1): D536-D541.
Abstract [ NAR ] [ PubMed ]  Full text [ PDF ] [ HTML ]

See the P2CS companions.

P2TF (Predicted Prokaryotic Transcription Factors) is available at www.p2tf.org. P2TF, a database of Transcription Factor (TF) proteins, contains the TFs of all available bacterial and archaeal genomes, and 43 microbial metagenomes.

P2RP (Predicted Prokaryotic Regulatory Proteins) is a freely accessible web server for regulatory proteins (RPs) prediction www.p2rp.org. The program can perform several types of analyses depending on the type of request, and provide detailed annotation of each RP gene including classification, sequence features, as well as functional domains.
Related databases and prediction tools :

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